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Vitamin C Protects Against Coronavirus
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Re: Vitamin C Protects Against Coronavirus
Here is some behind the scenes info. The wuhan coronavirus was much much more deadly by far than what western nations are experiencing.
Iran also may have recieved it on a massive scale too. Convenient...
China blamed US for the outbreak. China, Japan and I think singapore said it was created in the US.
Trump says he’s a war time president.
Saudi Arabia and Russia lowered oil prices which hurt US oil companies right at the most vulnerable time for US which was worst/fastest stock market crash in 90 years.
Dollar reserve currency status is at 109 to 110 years. Like clockwork, the previous reserve currencies get overthrown. Previous countries were 110 years long. 105 years, then 95 years, then 80 and another 80 years long.
US is a hair away from going to war with an Iraqi army division or something like that.
US bases are getting rocket attacks in Iraq by Iranian proxies.
North Korea still firing rockets. At one point, it was suggested in media North Korea may not exist as a country because of corona virus outbreak. Saying 20% of population will be dead. Was this a threat?
The US is deliberately bungling this lockdown and treatment options. They obviously want lockdown for some reason to be extended for a certain length of time. US is a big country. No reason why they couldn’t shut down portions of US that has cases. Tell people to wear homemade masks, workers get tested before working, etc.. My city of half million has almost no cases. But city is a ghost town.
There are others. Maybe half of these assumptions aren’t true but I do believe something going on behind the scenes.
Iran also may have recieved it on a massive scale too. Convenient...
China blamed US for the outbreak. China, Japan and I think singapore said it was created in the US.
Trump says he’s a war time president.
Saudi Arabia and Russia lowered oil prices which hurt US oil companies right at the most vulnerable time for US which was worst/fastest stock market crash in 90 years.
Dollar reserve currency status is at 109 to 110 years. Like clockwork, the previous reserve currencies get overthrown. Previous countries were 110 years long. 105 years, then 95 years, then 80 and another 80 years long.
US is a hair away from going to war with an Iraqi army division or something like that.
US bases are getting rocket attacks in Iraq by Iranian proxies.
North Korea still firing rockets. At one point, it was suggested in media North Korea may not exist as a country because of corona virus outbreak. Saying 20% of population will be dead. Was this a threat?
The US is deliberately bungling this lockdown and treatment options. They obviously want lockdown for some reason to be extended for a certain length of time. US is a big country. No reason why they couldn’t shut down portions of US that has cases. Tell people to wear homemade masks, workers get tested before working, etc.. My city of half million has almost no cases. But city is a ghost town.
There are others. Maybe half of these assumptions aren’t true but I do believe something going on behind the scenes.
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
Again, total assumptions just playing what if. Prime minister of canada, UK, germany in quarantine. Prince Charles too. I bet none of these old people will develop any health effects.
Trump has a dozen people behind him. Shaking hands and with some reporters still in the room as he does his press conference. Sounds like he’s not worried. Trump has the benefit of being able to run to an underground bunker in a minute if military action is taken. But for other important people in countries they are not so lucky. They have to go to their bunker as a precaution. So the leaders survive any military attack.
Anecdotal info saying important people are in their own home underground bunkers. Not living topside in their home enjoying life where they can still be quarantined from outsiders but they are below ground. Life sucks without windows. Why would they do that.
How does a war between countries that can destroy each other many times over in 21st century look like. Where their is globalization. Where each country dependant on the other. You starve the other side out.
Just like ancient wars, an army would circle the city. To starve the enemy into submission.
China is more dependant on the US and the west. Without us they would collapse. US and west also dependant but China would collapse first.
The one pro that China has is they don’t care if they kill 100 million of their own citizens. Whereas the US and west doesn’t have the stomach for a great depression. Where many would die.
Just a what if scenario. They say unemployment could be 30%. They could be correct. It has even been said this could last 12 months. Some that seem to have called every turn in this coronavirus have said to have a garden. A food supply.
Point being, I think everyone should brace themselves for the long term. Everyone thought WWI and WWII would be fast.
Trump has a dozen people behind him. Shaking hands and with some reporters still in the room as he does his press conference. Sounds like he’s not worried. Trump has the benefit of being able to run to an underground bunker in a minute if military action is taken. But for other important people in countries they are not so lucky. They have to go to their bunker as a precaution. So the leaders survive any military attack.
Anecdotal info saying important people are in their own home underground bunkers. Not living topside in their home enjoying life where they can still be quarantined from outsiders but they are below ground. Life sucks without windows. Why would they do that.
How does a war between countries that can destroy each other many times over in 21st century look like. Where their is globalization. Where each country dependant on the other. You starve the other side out.
Just like ancient wars, an army would circle the city. To starve the enemy into submission.
China is more dependant on the US and the west. Without us they would collapse. US and west also dependant but China would collapse first.
The one pro that China has is they don’t care if they kill 100 million of their own citizens. Whereas the US and west doesn’t have the stomach for a great depression. Where many would die.
Just a what if scenario. They say unemployment could be 30%. They could be correct. It has even been said this could last 12 months. Some that seem to have called every turn in this coronavirus have said to have a garden. A food supply.
Point being, I think everyone should brace themselves for the long term. Everyone thought WWI and WWII would be fast.
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
Here is a good post from another forum. He’s a nurse from Washington. It’s a good reminder to treat at the very first initial symptoms ASAP.
“We got absolutely hammered today. Starting to get the Covids in who got sick 2 to 3 weeks ago. This is how the progression seems to fit. Mild initial symptoms for two weeks or so, then sudden onset acute breathing difficulties almost out of nowhere, trip to ER, on a vent within minutes to hours of arrival. Common seeing people in their early 60's. Cardiomyopathy and cardiac arrest terminal. I am beat. Stay safe.”
“We got absolutely hammered today. Starting to get the Covids in who got sick 2 to 3 weeks ago. This is how the progression seems to fit. Mild initial symptoms for two weeks or so, then sudden onset acute breathing difficulties almost out of nowhere, trip to ER, on a vent within minutes to hours of arrival. Common seeing people in their early 60's. Cardiomyopathy and cardiac arrest terminal. I am beat. Stay safe.”
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
good article why ascorbic acid instead of liposomal.
“This article contains slides and notes from an exclusive webinar delivered to healthcare professionals on March 25, 2020. The central message in the presentation emphasized the oral form of ascorbic acid is a redox molecule that cannot be replaced by other antioxidants, perhaps even sodium ascorbate. The combination of high-dose oral ascorbic acid together with intravenous sodium ascorbate could significantly reduce the exponential increase of COVID-19 patients who require intensive care treatment after infection.
This article also includes a newly released study that identified the exact mechanisms used by SARS-CoV2 to destroy hemoglobin, resulting in cell-free heme that exacerbates ARDS.”
https://www.evolutamente.it/stop-ards-now-with-ascorbic-acid/?fbclid=IwAR1fzfnqPjjDUiND2ze6LlXfnqHjhO0e5i1xpFgZJWnzTNMNP-zevp38CW8
“This article contains slides and notes from an exclusive webinar delivered to healthcare professionals on March 25, 2020. The central message in the presentation emphasized the oral form of ascorbic acid is a redox molecule that cannot be replaced by other antioxidants, perhaps even sodium ascorbate. The combination of high-dose oral ascorbic acid together with intravenous sodium ascorbate could significantly reduce the exponential increase of COVID-19 patients who require intensive care treatment after infection.
This article also includes a newly released study that identified the exact mechanisms used by SARS-CoV2 to destroy hemoglobin, resulting in cell-free heme that exacerbates ARDS.”
https://www.evolutamente.it/stop-ards-now-with-ascorbic-acid/?fbclid=IwAR1fzfnqPjjDUiND2ze6LlXfnqHjhO0e5i1xpFgZJWnzTNMNP-zevp38CW8
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
This guy nails it 100%
https://www.facebook.com/69667273997/posts/10159492259718998/?d=n
https://www.facebook.com/69667273997/posts/10159492259718998/?d=n
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Re: Vitamin C Protects Against Coronavirus
Jdp710 wrote:good article why ascorbic acid instead of liposomal.
“This article contains slides and notes from an exclusive webinar delivered to healthcare professionals on March 25, 2020. The central message in the presentation emphasized the oral form of ascorbic acid is a redox molecule that cannot be replaced by other antioxidants, perhaps even sodium ascorbate. The combination of high-dose oral ascorbic acid together with intravenous sodium ascorbate could significantly reduce the exponential increase of COVID-19 patients who require intensive care treatment after infection.
This article also includes a newly released study that identified the exact mechanisms used by SARS-CoV2 to destroy hemoglobin, resulting in cell-free heme that exacerbates ARDS.”
https://www.evolutamente.it/stop-ards-now-with-ascorbic-acid/?fbclid=IwAR1fzfnqPjjDUiND2ze6LlXfnqHjhO0e5i1xpFgZJWnzTNMNP-zevp38CW8
This approach I've been using for years (8-9), and so barely remember what is the flu-like symptom. I probably had corono for coupe of days, and drip in 50-80g of vitamin c to do the justice.
I do think the author does not see the longevity downside to it, which is interference with copper, iron, which in the long term can influence health negatively...
I, for a thing am depended on high dose C intake as a result of my long term megadosing activities, I believe. Greying and less optional ceruloplasmin levels is a price to be paid for such N=1 learning...
However when house is burning, longevity is a secondary thought. What I mean is one can always megadose if has an acute need to get rid of viral infection...
It will do next to nothing to fungal issues as candida, but virus will disappear from the mechanisms already explained and pointed out in this thread...
Zaphod- Posts : 1236
Join date : 2011-11-19
Re: Vitamin C Protects Against Coronavirus
CausticSymmetry wrote:This guy nails it 100%
https://www.facebook.com/69667273997/posts/10159492259718998/?d=n
To add, they patent these pathogens to prevent others from doing research on that particular pathogen.
My take on why is it’s like what happened when national enquirer interviewed paid for and then makes porn star sign a non disclosure agreement about her times with Trump. Then they never release the interview. Preventing the story from ever being released because porn star signed an agreement that she can’t talk about it.
So basically patenting pathogens, you never know if this corona virus is as bad as it is or if the virus is worse. Like a potential dysinformation campaign.
As previously posted, it’s mostly a bacteria that’s causing this corona virus outbreak. The virus is a minor issue. More dysinformation. Everyone looking at a virus when it’s actually bacterial.
Here is good info why they might have shut down the economies of the world. Chinas supply lines are completely gone. China has been devastated! The US also created another crash as they always do when another wave of retirements (starting 2020) are happening. Just like saving and loan in late 80’s early 90’s. 9/11 and 2008. Were all waves of retirements occuring.
https://www.youtube.com/watch?v=MvECzVhAVcM
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
Zaphod wrote:Jdp710 wrote:good article why ascorbic acid instead of liposomal.
“This article contains slides and notes from an exclusive webinar delivered to healthcare professionals on March 25, 2020. The central message in the presentation emphasized the oral form of ascorbic acid is a redox molecule that cannot be replaced by other antioxidants, perhaps even sodium ascorbate. The combination of high-dose oral ascorbic acid together with intravenous sodium ascorbate could significantly reduce the exponential increase of COVID-19 patients who require intensive care treatment after infection.
This article also includes a newly released study that identified the exact mechanisms used by SARS-CoV2 to destroy hemoglobin, resulting in cell-free heme that exacerbates ARDS.”
https://www.evolutamente.it/stop-ards-now-with-ascorbic-acid/?fbclid=IwAR1fzfnqPjjDUiND2ze6LlXfnqHjhO0e5i1xpFgZJWnzTNMNP-zevp38CW8
This approach I've been using for years (8-9), and so barely remember what is the flu-like symptom. I probably had corono for coupe of days, and drip in 50-80g of vitamin c to do the justice.
I do think the author does not see the longevity downside to it, which is interference with copper, iron, which in the long term can influence health negatively...
I, for a thing am depended on high dose C intake as a result of my long term megadosing activities, I believe. Greying and less optional ceruloplasmin levels is a price to be paid for such N=1 learning...
However when house is burning, longevity is a secondary thought. What I mean is one can always megadose if has an acute need to get rid of viral infection...
It will do next to nothing to fungal issues as candida, but virus will disappear from the mechanisms already explained and pointed out in this thread...
I’m pretty sure this corona virus has been hitting the world in waves since november. My city was hit by in jan and feb. everyone like a mild cold. But I don’t think 5g is setup over here like wuhan china, nyc, west coast usa, lombardy Italy, etc..
They push 5g as it’s suppose to partly be a survelliance program.
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
This approach I've been using for years (8-9), and so barely remember what is the flu-like symptom. I probably had corono for coupe of days, and drip in 50-80g of vitamin c to do the justice.
Did you take the 50-80g vitamin C within 1 day?
imprisoned-radical- Posts : 493
Join date : 2011-08-09
Re: Vitamin C Protects Against Coronavirus
imprisoned-radical wrote:
This approach I've been using for years (8-9), and so barely remember what is the flu-like symptom. I probably had corono for coupe of days, and drip in 50-80g of vitamin c to do the justice.
Did you take the 50-80g vitamin C within 1 day?
Yes, to he exact it even did not take a full day to do a loading, but when i heard reverse fluid flow with ''bubbling'' my dose was reached...
I take 10g everyday.
Zaphod- Posts : 1236
Join date : 2011-11-19
Re: Vitamin C Protects Against Coronavirus
Closer to the truth
https://youtu.be/IIDths-UdDA
https://youtu.be/IIDths-UdDA
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Re: Vitamin C Protects Against Coronavirus
https://www.youtube.com/watch?v=bV53h7MCu9I&fbclid=IwAR0BifnyQtaZAHc2oRGe_sSFn3VxjQaPPsgAC1r_8XwrcQwYdhEN1S6ANyY
Zaphod- Posts : 1236
Join date : 2011-11-19
Re: Vitamin C Protects Against Coronavirus
Just want to say I really appreciate this forum and the information that is discussed. A lot of good info especially in a time like this. Thanks guys
bh1546- Posts : 198
Join date : 2011-04-21
Re: Vitamin C Protects Against Coronavirus
FOR IMMEDIATE RELEASE
Orthomolecular Medicine News Service, Apr 4, 2020
Sulforaphane as a Treatment for COVID-19
by Jihoon Kim D.C., D.A.C.N.B.
(OMNS Apr 4, 2020) Recent research suggests that a compound called 'sulforaphane' may have both a prophylactic and curative benefit against ARDS and SARS-CoV-2. Sulforaphane is found in cruciferous vegetables such as broccoli and kale. It is generated by damage to the plant and is involved in protecting the plant from insect predators. In mammals it activates the Nrf2 anti-inflammatory pathway, is a potent anti-bacterial agent, and has anti-cancer properties. Recent research shows that it can modulate epigenetic pathways in mammalian cells. [1]
Anti-viral properties
Sulforaphane has also been shown to have antiviral properties. Studies have shown that sulforaphane reduces viral load in the nose, increases NK cell production, displays antiviral activity against H1N1 Influenza virus, and can suppress replication of Hepatitis C Virus and inhibit HIV infection of macrophages through Nrf2. [2-5] Interestingly, heat shock proteins which are produced upon sulforaphane consumption are also known to have antiviral properties. [6]
Inducer of NRF2 anti-oxidant pathway
Sulforaphane may be particularly beneficial for the elderly. It is a powerful inducer of Nrf2, which regulates expression of more than 200 cytoprotective genes, including an antiviral pathway that impairs virus reproduction. [7,8] Nrf2 signaling is thought to decrease with age. According to one study, exercise induced Nrf2-signaling has been shown to be impaired in aging. [9] Sulforaphane was also shown to restore the age-related decrease of Th1 immunity in old mice. [10]
Sulforaphane treats ARDS
Animal and in vitro studies have shown that sulforaphane can mitigate the inflammatory damage to the lungs in ARDS. In one study, sulforaphane doubled the survivability of rabbits with ARDS. [11,12] Sulforaphane is also a potent inhibitor of NFkB, which is a master inducer of inflammation. [13] In one study, influenza virus-induced markers of inflammation were significantly lower in smokers after consumption of broccoli sprout homogenate. [14]
Protection for the lungs
Sulforaphane has a protective effect on the lungs. In a 12 week study in Qidong, China, consumption of sulforaphane was associated with immediate and sustained increase in urinary excretion of airborne pollutants, benzene 61% and acrolein 23%. [15] In another study, daily 100 æmol sulforaphane for 14 days was shown to improve the broncho-protective response in asthmatics. [16]
Cancer, diabetes
A plethora of studies have suggested sulforaphane has a mitigating effect on cancer, diabetes, and neurological disorders, all of which are risk factors of COVID-19 fatalities. [1,11,17]
Preparing sulforaphane
Broccoli sprouts contain the highest levels of precursors to sulforaphane: glucoraphanin and myrosinase. However, care must be taken because myrosinase is destroyed under heat. Broccoli sprouts must be thoroughly washed to prevent contamination by E. coli and Salmonella. Addition of myrosinase in the form of daikon radish, or mustard seed powder can increase the sulforaphane content. [18] Several supplements containing sulforaphane or its precursors glucoraphanin and myrosinase have been validated by multiple studies; those containing glucoraphanin alone have an average 10% bioavailability. [19,20] The suggested minimal adult dose is 4.4mg, based on the study in Qidong China that determined the level of sulforaphane needed to excrete benzene and acrolein. [15]
I am not an expert in the field infectious diseases or immunology and I certainly do not want to give people false hope. Currently, there are no clinical studies of sulphoraphane against COVID-19. But since there are no randomized controlled clinical trials of ANY treatment against COVID-19, we are left to utilize therapeutic approaches based on past research. Sulforaphane has been shown to be safe for consumption and is commercially available. I believe it may be an important treatment available to the average citizen in the current viral pandemic. Lastly, I hope this publication draws interest from experts and researchers in COVID-19 for further research and investigation.
(Dr. Jihoon Kim is a chiropractor and a diplomate of the American Chiropractic Neurology Board. Upon returning to South Korea, he became an assistant professor at Seoul's Chaum Anti-Aging Center, and director of a facility for children with autism spectrum disorders. Dr. Kim is currently a professor at Organic Culture, also in Seoul.)
References:
1. Hyun TK. (2020) A recent overview on sulforaphane as a dietary epigenetic modulator. EXCLI J. 19:131-134. https://www.ncbi.nlm.nih.gov/pubmed/32194360.
2. M ller L, Meyer M, Bauer RN et al. (2016) Effect of Broccoli Sprouts and Live Attenuated Influenza Virus on Peripheral Blood Natural Killer Cells: A Randomized, Double-Blind Study. PLoS One. 11(1):e0147742. https://www.ncbi.nlm.nih.gov/pubmed/26820305.
3. Li Z, Liu Y, Fang Z et al. (2019) Natural Sulforaphane From Broccoli Seeds Against Influenza A Virus Replication in MDCK Cells. Natural Product Communications, June 2019: 1-8. https://journals.sagepub.com/doi/pdf/10.1177/1934578X19858221.
4. Yu JS Chen WC, Tseng CK et al. (2016) Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway. PLoS One. 11(3):e0152236. https://www.ncbi.nlm.nih.gov/pubmed/27023634.
5. Furuya AK, Sharifi HJ, Jellinger RM, et al. (2016) Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. PLoS Pathog. 12(4):e1005581. https://www.ncbi.nlm.nih.gov/pubmed/27093399.
6. Tsan MF, Gao B. (2009) Heat shock proteins and immune system. J Leukoc Biol. 85:905-910. https://www.ncbi.nlm.nih.gov/pubmed/19276179.
7. Houghton CA (2019) Sulforaphane: Its "Coming of Age" as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019:2716870. https://www.ncbi.nlm.nih.gov/pubmed/31737167.
8. Wyler E, Franke V, Menegatti J et al. (2019) Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program. Nat Commun. 10:4878. https://www.ncbi.nlm.nih.gov/pubmed/31653857.
9. Done AJ, Gage MJ, Nieto NC, Traustad¢ttir T. (2016) Exercise-induced Nrf2-signaling is impaired in aging. Free Radic Biol Med. 96:130-8. https://www.ncbi.nlm.nih.gov/pubmed/27109910.
10. Kim HJ, Barajas B, Wang M, Nel AE. (2008) Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells. J Allergy Clin Immunol. 121:1255-1261.e7. https://www.ncbi.nlm.nih.gov/pubmed/18325578.
11. Patel V, Dial K, Wu J, Gauthier AG. (2020) Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1. Int J Mol Sci. ;21(3). pii:E977. https://www.ncbi.nlm.nih.gov/pubmed/32024151.
12. Sun Z, Niu Z, Wu S, Shan S. (2018) Protective mechanism of sulforaphane in Nrf2 and anti-lung injury in ARDS rabbits. Exp Ther Med. 15:4911-4915. https://www.ncbi.nlm.nih.gov/pubmed/29805514.
13. Heiss E, Herhaus C, Klimo K, Bartsch H, Gerh"user C. (2001) Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. J Biol Chem. 276:32008-32015. https://www.ncbi.nlm.nih.gov/pubmed/11410599.
14. Noah TL, Zhang H, Zhou H, Glista-Baker E, et al. (2014) Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study. PLoS One. 9(6):e98671. https://www.ncbi.nlm.nih.gov/pubmed/24910991.
15. Kensler TW, Ng D, Carmella SG et al, (2012) Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis. 33:101-107. https://www.ncbi.nlm.nih.gov/pubmed/22045030.
16. Brown RH, Reynolds C, Brooker A, Talalay P, Fahey JW. (2015) Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways. Respir Res. 16:106. https://www.ncbi.nlm.nih.gov/pubmed/26369337.
17. Sun Y, Zhou S, Guo H, et al. (2020) Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function. Metabolism. 102:154002. https://www.ncbi.nlm.nih.gov/pubmed/31706979.
18. Fahey JW, Holtzclaw WD, Wehage SL, et al. (2015) Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase. PLoS One. 10(11):e0140963. https://www.ncbi.nlm.nih.gov/pubmed/26524341.
19. Fahey JW, Wade KL, Stephenson KK, et al. (2019) Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration. Nutrients. 11(7). pii: E1489. https://www.ncbi.nlm.nih.gov/pubmed/31261930.
20. Yagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW. (2019) Broccoli or Sulforaphane: Is It the Source or Dose That Matters? Molecules. 24(19). pii: E3593. https://www.ncbi.nlm.nih.gov/pubmed/31590459.
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Orthomolecular Medicine News Service, Apr 4, 2020
Sulforaphane as a Treatment for COVID-19
by Jihoon Kim D.C., D.A.C.N.B.
(OMNS Apr 4, 2020) Recent research suggests that a compound called 'sulforaphane' may have both a prophylactic and curative benefit against ARDS and SARS-CoV-2. Sulforaphane is found in cruciferous vegetables such as broccoli and kale. It is generated by damage to the plant and is involved in protecting the plant from insect predators. In mammals it activates the Nrf2 anti-inflammatory pathway, is a potent anti-bacterial agent, and has anti-cancer properties. Recent research shows that it can modulate epigenetic pathways in mammalian cells. [1]
Anti-viral properties
Sulforaphane has also been shown to have antiviral properties. Studies have shown that sulforaphane reduces viral load in the nose, increases NK cell production, displays antiviral activity against H1N1 Influenza virus, and can suppress replication of Hepatitis C Virus and inhibit HIV infection of macrophages through Nrf2. [2-5] Interestingly, heat shock proteins which are produced upon sulforaphane consumption are also known to have antiviral properties. [6]
Inducer of NRF2 anti-oxidant pathway
Sulforaphane may be particularly beneficial for the elderly. It is a powerful inducer of Nrf2, which regulates expression of more than 200 cytoprotective genes, including an antiviral pathway that impairs virus reproduction. [7,8] Nrf2 signaling is thought to decrease with age. According to one study, exercise induced Nrf2-signaling has been shown to be impaired in aging. [9] Sulforaphane was also shown to restore the age-related decrease of Th1 immunity in old mice. [10]
Sulforaphane treats ARDS
Animal and in vitro studies have shown that sulforaphane can mitigate the inflammatory damage to the lungs in ARDS. In one study, sulforaphane doubled the survivability of rabbits with ARDS. [11,12] Sulforaphane is also a potent inhibitor of NFkB, which is a master inducer of inflammation. [13] In one study, influenza virus-induced markers of inflammation were significantly lower in smokers after consumption of broccoli sprout homogenate. [14]
Protection for the lungs
Sulforaphane has a protective effect on the lungs. In a 12 week study in Qidong, China, consumption of sulforaphane was associated with immediate and sustained increase in urinary excretion of airborne pollutants, benzene 61% and acrolein 23%. [15] In another study, daily 100 æmol sulforaphane for 14 days was shown to improve the broncho-protective response in asthmatics. [16]
Cancer, diabetes
A plethora of studies have suggested sulforaphane has a mitigating effect on cancer, diabetes, and neurological disorders, all of which are risk factors of COVID-19 fatalities. [1,11,17]
Preparing sulforaphane
Broccoli sprouts contain the highest levels of precursors to sulforaphane: glucoraphanin and myrosinase. However, care must be taken because myrosinase is destroyed under heat. Broccoli sprouts must be thoroughly washed to prevent contamination by E. coli and Salmonella. Addition of myrosinase in the form of daikon radish, or mustard seed powder can increase the sulforaphane content. [18] Several supplements containing sulforaphane or its precursors glucoraphanin and myrosinase have been validated by multiple studies; those containing glucoraphanin alone have an average 10% bioavailability. [19,20] The suggested minimal adult dose is 4.4mg, based on the study in Qidong China that determined the level of sulforaphane needed to excrete benzene and acrolein. [15]
I am not an expert in the field infectious diseases or immunology and I certainly do not want to give people false hope. Currently, there are no clinical studies of sulphoraphane against COVID-19. But since there are no randomized controlled clinical trials of ANY treatment against COVID-19, we are left to utilize therapeutic approaches based on past research. Sulforaphane has been shown to be safe for consumption and is commercially available. I believe it may be an important treatment available to the average citizen in the current viral pandemic. Lastly, I hope this publication draws interest from experts and researchers in COVID-19 for further research and investigation.
(Dr. Jihoon Kim is a chiropractor and a diplomate of the American Chiropractic Neurology Board. Upon returning to South Korea, he became an assistant professor at Seoul's Chaum Anti-Aging Center, and director of a facility for children with autism spectrum disorders. Dr. Kim is currently a professor at Organic Culture, also in Seoul.)
References:
1. Hyun TK. (2020) A recent overview on sulforaphane as a dietary epigenetic modulator. EXCLI J. 19:131-134. https://www.ncbi.nlm.nih.gov/pubmed/32194360.
2. M ller L, Meyer M, Bauer RN et al. (2016) Effect of Broccoli Sprouts and Live Attenuated Influenza Virus on Peripheral Blood Natural Killer Cells: A Randomized, Double-Blind Study. PLoS One. 11(1):e0147742. https://www.ncbi.nlm.nih.gov/pubmed/26820305.
3. Li Z, Liu Y, Fang Z et al. (2019) Natural Sulforaphane From Broccoli Seeds Against Influenza A Virus Replication in MDCK Cells. Natural Product Communications, June 2019: 1-8. https://journals.sagepub.com/doi/pdf/10.1177/1934578X19858221.
4. Yu JS Chen WC, Tseng CK et al. (2016) Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway. PLoS One. 11(3):e0152236. https://www.ncbi.nlm.nih.gov/pubmed/27023634.
5. Furuya AK, Sharifi HJ, Jellinger RM, et al. (2016) Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. PLoS Pathog. 12(4):e1005581. https://www.ncbi.nlm.nih.gov/pubmed/27093399.
6. Tsan MF, Gao B. (2009) Heat shock proteins and immune system. J Leukoc Biol. 85:905-910. https://www.ncbi.nlm.nih.gov/pubmed/19276179.
7. Houghton CA (2019) Sulforaphane: Its "Coming of Age" as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019:2716870. https://www.ncbi.nlm.nih.gov/pubmed/31737167.
8. Wyler E, Franke V, Menegatti J et al. (2019) Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program. Nat Commun. 10:4878. https://www.ncbi.nlm.nih.gov/pubmed/31653857.
9. Done AJ, Gage MJ, Nieto NC, Traustad¢ttir T. (2016) Exercise-induced Nrf2-signaling is impaired in aging. Free Radic Biol Med. 96:130-8. https://www.ncbi.nlm.nih.gov/pubmed/27109910.
10. Kim HJ, Barajas B, Wang M, Nel AE. (2008) Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells. J Allergy Clin Immunol. 121:1255-1261.e7. https://www.ncbi.nlm.nih.gov/pubmed/18325578.
11. Patel V, Dial K, Wu J, Gauthier AG. (2020) Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1. Int J Mol Sci. ;21(3). pii:E977. https://www.ncbi.nlm.nih.gov/pubmed/32024151.
12. Sun Z, Niu Z, Wu S, Shan S. (2018) Protective mechanism of sulforaphane in Nrf2 and anti-lung injury in ARDS rabbits. Exp Ther Med. 15:4911-4915. https://www.ncbi.nlm.nih.gov/pubmed/29805514.
13. Heiss E, Herhaus C, Klimo K, Bartsch H, Gerh"user C. (2001) Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. J Biol Chem. 276:32008-32015. https://www.ncbi.nlm.nih.gov/pubmed/11410599.
14. Noah TL, Zhang H, Zhou H, Glista-Baker E, et al. (2014) Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study. PLoS One. 9(6):e98671. https://www.ncbi.nlm.nih.gov/pubmed/24910991.
15. Kensler TW, Ng D, Carmella SG et al, (2012) Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis. 33:101-107. https://www.ncbi.nlm.nih.gov/pubmed/22045030.
16. Brown RH, Reynolds C, Brooker A, Talalay P, Fahey JW. (2015) Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways. Respir Res. 16:106. https://www.ncbi.nlm.nih.gov/pubmed/26369337.
17. Sun Y, Zhou S, Guo H, et al. (2020) Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function. Metabolism. 102:154002. https://www.ncbi.nlm.nih.gov/pubmed/31706979.
18. Fahey JW, Holtzclaw WD, Wehage SL, et al. (2015) Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase. PLoS One. 10(11):e0140963. https://www.ncbi.nlm.nih.gov/pubmed/26524341.
19. Fahey JW, Wade KL, Stephenson KK, et al. (2019) Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration. Nutrients. 11(7). pii: E1489. https://www.ncbi.nlm.nih.gov/pubmed/31261930.
20. Yagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW. (2019) Broccoli or Sulforaphane: Is It the Source or Dose That Matters? Molecules. 24(19). pii: E3593. https://www.ncbi.nlm.nih.gov/pubmed/31590459.
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Re: Vitamin C Protects Against Coronavirus
This is a similar video as posted previously. Talks how certain times of increased EMF exposure and pandemics occur shortly after. One that wasn’t discussed was 1889. Had 4 year pandemic when electricity was rolled out.
https://www.youtube.com/watch?v=xEjAahJfnSI&t=325s
https://www.youtube.com/watch?v=xEjAahJfnSI&t=325s
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
From the book The Invisible Rainbow – Informational Summary
"In 2001, Canadian astronomer Ken Tapping showed that the influenza pandemics
over the previous three centuries correlated with peaks in solar magnetic activity, on an 11-
year cycle. It has also been found that some outbreaks of influenza spread over enormous
areas in just a few days – a fact that is difficult to explain by contagion from one person to
another. Also, numerous experiments seeking to prove direct contagion through close
contact, droplets of mucus or other processes have proved fruitless.
From 1933 to the present day, virologists have been unable to present any
experimental study proving that influenza spreads through normal contact between people.
All attempts to do so have met with failure."
https://www.5gexposed.com/wp-content/uploads/2019/04/English-Summary-of-The-Invisible-Rainbow-A-History-of-Electricity-and-Life-3.pdf
"In 2001, Canadian astronomer Ken Tapping showed that the influenza pandemics
over the previous three centuries correlated with peaks in solar magnetic activity, on an 11-
year cycle. It has also been found that some outbreaks of influenza spread over enormous
areas in just a few days – a fact that is difficult to explain by contagion from one person to
another. Also, numerous experiments seeking to prove direct contagion through close
contact, droplets of mucus or other processes have proved fruitless.
From 1933 to the present day, virologists have been unable to present any
experimental study proving that influenza spreads through normal contact between people.
All attempts to do so have met with failure."
https://www.5gexposed.com/wp-content/uploads/2019/04/English-Summary-of-The-Invisible-Rainbow-A-History-of-Electricity-and-Life-3.pdf
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Re: Vitamin C Protects Against Coronavirus
Since there so much positive mention of Hydroxychloroquine, would it be a good idea to find natural alternative ready at our homes or perhaps add to our natural preventative stack?
From what I have heard Quinine is essential the same thing. Apparently tonic water or even Schweppes is rich in quinine. So is it a good idea to buy this? Will it work? Also I can't seem to find this online. Maybe because they banned it in the 90s or something as a supplement.
When I google, the PQQ, which I actually got in the past, comes up. Is PQQ Quinine? Any links to Quinine online?
From what I have heard Quinine is essential the same thing. Apparently tonic water or even Schweppes is rich in quinine. So is it a good idea to buy this? Will it work? Also I can't seem to find this online. Maybe because they banned it in the 90s or something as a supplement.
When I google, the PQQ, which I actually got in the past, comes up. Is PQQ Quinine? Any links to Quinine online?
Last edited by MikeGore on Sat Apr 11, 2020 7:05 pm; edited 1 time in total
MikeGore- Posts : 803
Join date : 2010-05-24
Re: Vitamin C Protects Against Coronavirus
MikeGore wrote:Since there so much positive mention of Hydroxychloroquine, would it be a good idea to find natural alternative ready at our homes or perhaps add to our natural preventative stack?
From what I have heard Quinine is essential the same thing. Apparently tonic water or even Schweppes is rich in quinine. So is it a good idea to buy this? Will it work? Also I can seem to find this online. Maybe because they banned it in the 90s or something as a supplement.
When I google, the PQQ, which I actually got in the past, comes up. Is PQQ Quinine? Any links to Quinine online?
Yes, technically tonic water contains quinine--well usually, because it's added to tonic water, but usage has been banned in some countries.
One could easily buy the antimalarial Artemisinin.
https://academic.oup.com/cid/article/47/6/804/325924
A couple of notes here, Artemisinin should be taken without antioxidants for it to work properly.
Also if Hydroxychloroquine is used, zinc is a necessary companion for it to work effectively.
Artemisinin can be found here:
https://amzn.to/2JTXMjf
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Re: Vitamin C Protects Against Coronavirus
Thank you CS.
Interestingly I had a wordwood supplement lying around in my house, but didn't know it had anything to do with quinine. It'll come in handy now. Cheers.
Interestingly I had a wordwood supplement lying around in my house, but didn't know it had anything to do with quinine. It'll come in handy now. Cheers.
MikeGore- Posts : 803
Join date : 2010-05-24
Re: Vitamin C Protects Against Coronavirus
MikeGore wrote:Since there so much positive mention of Hydroxychloroquine, would it be a good idea to find natural alternative ready at our homes or perhaps add to our natural preventative stack?
From what I have heard Quinine is essential the same thing. Apparently tonic water or even Schweppes is rich in quinine. So is it a good idea to buy this? Will it work? Also I can't seem to find this online. Maybe because they banned it in the 90s or something as a supplement.
When I google, the PQQ, which I actually got in the past, comes up. Is PQQ Quinine? Any links to Quinine online?
I think the natural alternative is definitely Quercetin phytosome and Zinc
cryo458- Posts : 4
Join date : 2017-07-08
Re: Vitamin C Protects Against Coronavirus
cryo458 wrote:MikeGore wrote:Since there so much positive mention of Hydroxychloroquine, would it be a good idea to find natural alternative ready at our homes or perhaps add to our natural preventative stack?
From what I have heard Quinine is essential the same thing. Apparently tonic water or even Schweppes is rich in quinine. So is it a good idea to buy this? Will it work? Also I can't seem to find this online. Maybe because they banned it in the 90s or something as a supplement.
When I google, the PQQ, which I actually got in the past, comes up. Is PQQ Quinine? Any links to Quinine online?
I think the natural alternative is definitely Quercetin phytosome and Zinc
Pyrroloquinoline quinone (PQQ) is not quinine, but yes forms of Quercetin add to the many safe options.
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Re: Vitamin C Protects Against Coronavirus
Everyone here is extremely ill. Worse than bad flu. Imagine your worst health ailment and experience you’ve had and x it by 2 or 3 or 4. That’s what it’s like. The DIY pyroenergen which is mos5 powerful anti viral method known knocks out the ver6 bad breathing problems. You feel better for 12 or 24 hours only for it to come back. Today, went through all my various supplements which I have dozens of. Grape seed extract appears to be the best so far. Has antiviral properties. This is one I use. So far I recommend it unless it was coincidence. Take much more than directed on bottle. https://smile.amazon.com/gp/product/B005HZP6UW/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
Jdp710 wrote:Everyone here is extremely ill. Worse than bad flu. Imagine your worst health ailment and experience you’ve had and x it by 2 or 3 or 4. That’s what it’s like. The DIY pyroenergen which is mos5 powerful anti viral method known knocks out the ver6 bad breathing problems. You feel better for 12 or 24 hours only for it to come back. Today, went through all my various supplements which I have dozens of. Grape seed extract appears to be the best so far. Has antiviral properties. This is one I use. So far I recommend it unless it was coincidence. Take much more than directed on bottle. https://smile.amazon.com/gp/product/B005HZP6UW/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1
Can you elaborate ?Here means your home ? Work place ?
Are you ill also ?
I pray for a speedy recovery.
Nuada- Posts : 430
Join date : 2008-09-28
Re: Vitamin C Protects Against Coronavirus
a Very bad storm came through this city about 5 days ago. Everyone got sick right away. Like it was a trigger. Family and people in the city.
My breathing was very bad. Oxygen meter reading was as low as 83 and heart rate 115-125. Head very bad. Some other minor issues.
Other family member had coughing and typical flu symptoms. No big deal.
Other family member couldn’t walk more than a couple steps. Couldn’t stand would probably fall. Had to be picked up and pushed around in chair. No energy. Eyes beat red. Very bad flu. Took a bunch of vitamin c. No improvement. Should have taken it earlier.
I started taking supplements. Trying to find best. Grape seed extract worked. Pyroenergen works. But suspect it will come back. Will use it every night now. Rather than waiting for symptoms. Pyroenergen raises cell voltage which repels virus. I don’t have an antibiotic. Maybe why this keeps coming back over and over.
Seems this bug lingers ... mild symptoms for a long time and Then hits very fast. Flu you know when you caught it and then ramps up and then disappears. This doesn’t. Behaves different.
I read 1/5 in NYC probably have it now. Chicago 30% already have antibodies (prior infection). I think many people if they can’t get past a flu that they’ve had that is 2-4x worse than they ever had before, that’s where they die or become hospitalized.
My breathing was very bad. Oxygen meter reading was as low as 83 and heart rate 115-125. Head very bad. Some other minor issues.
Other family member had coughing and typical flu symptoms. No big deal.
Other family member couldn’t walk more than a couple steps. Couldn’t stand would probably fall. Had to be picked up and pushed around in chair. No energy. Eyes beat red. Very bad flu. Took a bunch of vitamin c. No improvement. Should have taken it earlier.
I started taking supplements. Trying to find best. Grape seed extract worked. Pyroenergen works. But suspect it will come back. Will use it every night now. Rather than waiting for symptoms. Pyroenergen raises cell voltage which repels virus. I don’t have an antibiotic. Maybe why this keeps coming back over and over.
Seems this bug lingers ... mild symptoms for a long time and Then hits very fast. Flu you know when you caught it and then ramps up and then disappears. This doesn’t. Behaves different.
I read 1/5 in NYC probably have it now. Chicago 30% already have antibodies (prior infection). I think many people if they can’t get past a flu that they’ve had that is 2-4x worse than they ever had before, that’s where they die or become hospitalized.
Jdp710- Posts : 470
Join date : 2017-04-09
Re: Vitamin C Protects Against Coronavirus
Jdp710 wrote:a Very bad storm came through this city about 5 days ago. Everyone got sick right away. Like it was a trigger. Family and people in the city.
My breathing was very bad. Oxygen meter reading was as low as 83 and heart rate 115-125. Head very bad. Some other minor issues.
Other family member had coughing and typical flu symptoms. No big deal.
Other family member couldn’t walk more than a couple steps. Couldn’t stand would probably fall. Had to be picked up and pushed around in chair. No energy. Eyes beat red. Very bad flu. Took a bunch of vitamin c. No improvement. Should have taken it earlier.
I started taking supplements. Trying to find best. Grape seed extract worked. Pyroenergen works. But suspect it will come back. Will use it every night now. Rather than waiting for symptoms. Pyroenergen raises cell voltage which repels virus. I don’t have an antibiotic. Maybe why this keeps coming back over and over.
Seems this bug lingers ... mild symptoms for a long time and Then hits very fast. Flu you know when you caught it and then ramps up and then disappears. This doesn’t. Behaves different.
I read 1/5 in NYC probably have it now. Chicago 30% already have antibodies (prior infection). I think many people if they can’t get past a flu that they’ve had that is 2-4x worse than they ever had before, that’s where they die or become hospitalized.
I'm sorry to hear that.
You mentioned antibiotics. But aren't they useless in cases with Covid induced pneumonia ?
As for Covid it is pretty weird that some people have mild symptoms(majority) and some extreme. Well at least you found some sort of a remedy, or a way to at least combat the virus.
In early 2016, like January 5th or something I had a terrible flu(at least I thought it was). High fever, vomiting, aching all over the body, including severe head aches and dizzyness. I didn't have energy to get up, I thought it would go away and didn't see a doctor and didn't take any medicine. My mom came a few days later and brought seasonal flu pills, which turns out they are mostly effective within the 48 hour period. So they didn't do much. In the 2nd night I made my self sweat and in the morning I felt slightly better. But then it came back. I was lucky my mom actually took care of me for a few days. It took at least 5-6 days for me to get up and sit infront of a computer. Symptoms were less severe, but I started coughing by then. And it took a good week more for the cough and weakness to go away. So about 2 weeks in total. 5-6 days pretty severe, rest not so much. I looked into WHO's website and there had been MERS outbreaks through out 2015.
So I'm suspecting that's what I got. And that is a Corona family virus. I'm not sure how bad the current one is compared to that but I'd hate to go over the same thing again.
Nuada- Posts : 430
Join date : 2008-09-28
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