Search
Check Out Our Sponsors
Latest topics
PGD2 involved in erections. Could this be the link between masturbating and baldness?
+14
sanderson
ngb
Espio
Hairbeback
alphadelta
RisingFist
4039
LawOfThelema
theseeker86
Duketronix
SlowMoe
DeadlyDevice
AS54
Xenon
18 posters
Page 1 of 2
Page 1 of 2 • 1, 2
PGD2 involved in erections. Could this be the link between masturbating and baldness?
I'm really tired right now, so excuse me for this half assed thread, BUT I found a pubmed study about PGD2 possibly playing a role in erectile function. I just wanted to point out that elevated levels of PGD2 have been found in the scalps of balding men, so it may be that excessive masturbation causes this prostaglandin to deposit within the scalp. Maybe.
Other studies also stated that DHT is likely the trigger in a surge in PGD2, and as we know, DHT is involved in erections.
"Prostaglandin D(2) (PGD(2)) binds to specific G-protein coupled receptors (DP) and induces smooth muscle relaxation by stimulating the synthesis of intracellular cAMP. In this study, we examined the role of PGD(2) and DP receptors in regulating human penile smooth muscle contractility. We determined that human corpus cavernosum tissue and smooth muscle cells in culture expressed functional DP receptor and lipocalin-like prostaglandin D synthase by reverse-transcribed polymerase chain reaction (RT-PCR). Functional PGD synthase activity was confirmed by the synthesis of PGD(2) in human corpus cavernosum smooth muscle cells upon addition of exogenous arachidonic acid. Organ bath preparations of human corpus cavernosum tissue strips, contracted with phenylephrine, relaxed in a dose-dependent fashion to either PGD(2) or the DP selective agonist BW245C. Cultures of human corpus cavernosum smooth muscle cells treated with BW245C showed a two-fold increase in cAMP synthesis. These data are consistent with the expression of functional DP receptors in human corpus cavernosum. This suggests the presence of an intact prostanoid autocrine system that may play a role in regulating penile erectile function."
http://www.ncbi.nlm.nih.gov/pubmed/12494276
Other studies also stated that DHT is likely the trigger in a surge in PGD2, and as we know, DHT is involved in erections.
"Prostaglandin D(2) (PGD(2)) binds to specific G-protein coupled receptors (DP) and induces smooth muscle relaxation by stimulating the synthesis of intracellular cAMP. In this study, we examined the role of PGD(2) and DP receptors in regulating human penile smooth muscle contractility. We determined that human corpus cavernosum tissue and smooth muscle cells in culture expressed functional DP receptor and lipocalin-like prostaglandin D synthase by reverse-transcribed polymerase chain reaction (RT-PCR). Functional PGD synthase activity was confirmed by the synthesis of PGD(2) in human corpus cavernosum smooth muscle cells upon addition of exogenous arachidonic acid. Organ bath preparations of human corpus cavernosum tissue strips, contracted with phenylephrine, relaxed in a dose-dependent fashion to either PGD(2) or the DP selective agonist BW245C. Cultures of human corpus cavernosum smooth muscle cells treated with BW245C showed a two-fold increase in cAMP synthesis. These data are consistent with the expression of functional DP receptors in human corpus cavernosum. This suggests the presence of an intact prostanoid autocrine system that may play a role in regulating penile erectile function."
http://www.ncbi.nlm.nih.gov/pubmed/12494276
Xenon- Posts : 1601
Join date : 2012-05-03
Location : Alpha Draconis
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
So if I can just expand upon the above information...
Each time we masturbate, there is a surge in PGD2, as it plays a role in erectile function. At the same time blood pressure to the scalp increases (you may have noticed your temples becoming really hot due to increased blood flow). What may happen at this point is, PGD2 might be carried to the scalp where it binds to receptors in follicles and it either inflames them or programs them to stop growing hair.
Each time we masturbate, there is a surge in PGD2, as it plays a role in erectile function. At the same time blood pressure to the scalp increases (you may have noticed your temples becoming really hot due to increased blood flow). What may happen at this point is, PGD2 might be carried to the scalp where it binds to receptors in follicles and it either inflames them or programs them to stop growing hair.
Xenon- Posts : 1601
Join date : 2012-05-03
Location : Alpha Draconis
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
I get erections throughout the night whenever I dream, regardless of whether the dream is sexual. Many men do actually. With the apnea, I tend to wake up pretty frequently through the night, and each time, it never fails.
AS54- Posts : 2367
Join date : 2011-08-12
Age : 35
Location : MI
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
yeh, I guess it can't be helped in that respect, but the issue is down to the act of masturbating in itself. As I said, when you masturbate, heart rate increases and there is concentrated bloodflow to the scalp. When this happens, it's likely that elevated levels of PGD2 are concentrated to the scalp also (especially if you jerk off for 2 hours non stop :p).
And I know people will ask the inevitable, 'why aren't all porn stars bald if this is the case?'
I'm not sure at this point, but it could be that certain guys have PGD2 receptors in their scalps, whereas some may not. One thing I can attest to, over masturbating, in my own case, plus testimonies from countless guys, leaves me in no doubt that it does play a role in MPB.
And I know people will ask the inevitable, 'why aren't all porn stars bald if this is the case?'
I'm not sure at this point, but it could be that certain guys have PGD2 receptors in their scalps, whereas some may not. One thing I can attest to, over masturbating, in my own case, plus testimonies from countless guys, leaves me in no doubt that it does play a role in MPB.
Xenon- Posts : 1601
Join date : 2012-05-03
Location : Alpha Draconis
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Lol, I know no one wants to hear it.
But it's a possibility.
"Why aren't all porn stars bald?"
Orgasms from masturbation are not the same thing as orgasms from sex, this is shown by the fact that there is 4x more prolactin released during sex.
Not to say prolactin is good for hair, far from it, but just goes to show there is a lot more to this picture than meets the eye. There are probably other hormones that behave differently during sex vs masturbation.
Sooo... good thing I joined NoFap.
But it's a possibility.
"Why aren't all porn stars bald?"
Orgasms from masturbation are not the same thing as orgasms from sex, this is shown by the fact that there is 4x more prolactin released during sex.
Not to say prolactin is good for hair, far from it, but just goes to show there is a lot more to this picture than meets the eye. There are probably other hormones that behave differently during sex vs masturbation.
Sooo... good thing I joined NoFap.
DeadlyDevice- Posts : 276
Join date : 2012-12-18
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Or maybe pornstars' huge units are a testament to the magnitude of the vasculare on their extremeties. I mean most of those guys are like 6 inches flaacid
?
?
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
...anyone can make their penis bigger with exercise. It just takes patience and commitment. I'm living proof and there are many others/communities of people online doing this.
...weirdly so many men I've told about it refuse to believe it is possible..... Which is fine by me. I'll keep growing while the average stays lower, sounds good!
...weirdly so many men I've told about it refuse to believe it is possible..... Which is fine by me. I'll keep growing while the average stays lower, sounds good!
Duketronix- Posts : 532
Join date : 2012-06-08
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
DAMNIT!! I had written a big post and somehow it got lost...
Basically the gist was if you get in touch with your sexuality there are ways to masturbate and have sex that don't give you any of the negative feelings you're talking about. I have orgasms that make my whole body vibrate for up to half an hour and I feel it especially in my scalp and cheeks. They make me giddy and I laugh. It almost feels like when your feet fall asleep but the opposite end of the spectrum. IMO one needs to refine their relationship with themselves sexually and then it becomes a TOTALLY different game/ball park etc. I can have orgasms without ejaculating and and sometimes can achieve what I never would have believed was possible from an orgasm before. IMO the ejaculatory orgasm though fun is really not a FULL orgasm, it feels great and you ahve muscle contraction etc... but well it's hard to describe what lays beyond it. But when you experience it you'll know.
anyway masturbation is fine IMO/IME if not done in an immature way. Exercise your mind (not using porn) and put yourself INTO the fantasy and that can become VERY intense and good. I still let myself ejaculate every 4-5 days and only with a partner simply because it's good for the prostate and well.. its fun! but again I no longer get those types of negative physical symptoms you're talking about. PGD2? who knows? Probably it's there but maybe somthing else is happening with it.... idunno.... But I think everyone should explore themselves more than most do.
Basically the gist was if you get in touch with your sexuality there are ways to masturbate and have sex that don't give you any of the negative feelings you're talking about. I have orgasms that make my whole body vibrate for up to half an hour and I feel it especially in my scalp and cheeks. They make me giddy and I laugh. It almost feels like when your feet fall asleep but the opposite end of the spectrum. IMO one needs to refine their relationship with themselves sexually and then it becomes a TOTALLY different game/ball park etc. I can have orgasms without ejaculating and and sometimes can achieve what I never would have believed was possible from an orgasm before. IMO the ejaculatory orgasm though fun is really not a FULL orgasm, it feels great and you ahve muscle contraction etc... but well it's hard to describe what lays beyond it. But when you experience it you'll know.
anyway masturbation is fine IMO/IME if not done in an immature way. Exercise your mind (not using porn) and put yourself INTO the fantasy and that can become VERY intense and good. I still let myself ejaculate every 4-5 days and only with a partner simply because it's good for the prostate and well.. its fun! but again I no longer get those types of negative physical symptoms you're talking about. PGD2? who knows? Probably it's there but maybe somthing else is happening with it.... idunno.... But I think everyone should explore themselves more than most do.
Duketronix- Posts : 532
Join date : 2012-06-08
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Duketronix wrote:I have orgasms that make my whole body vibrate for up to half an hour...
How can I achieve this lol
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Duketronix wrote:...anyone can make their penis bigger with exercise. It just takes patience and commitment. I'm living proof and there are many others/communities of people online doing this.
...weirdly so many men I've told about it refuse to believe it is possible..... Which is fine by me. I'll keep growing while the average stays lower, sounds good!
I wouldn't mind increasing my thickness, I'm not pencil thin but the extra girth could be nice.
theseeker86- Posts : 518
Join date : 2011-05-05
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Get hung like a killer whale:
Xenon- Posts : 1601
Join date : 2012-05-03
Location : Alpha Draconis
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
theseeker86 wrote:Duketronix wrote:...anyone can make their penis bigger with exercise. It just takes patience and commitment. I'm living proof and there are many others/communities of people online doing this.
...weirdly so many men I've told about it refuse to believe it is possible..... Which is fine by me. I'll keep growing while the average stays lower, sounds good!
I wouldn't mind increasing my thickness, I'm not pencil thin but the extra girth could be nice.
theres a thread on how to do this at the other forum. it involves injections. lol
LawOfThelema- Posts : 949
Join date : 2012-05-17
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
FACK!!! I just did it again! somethings wrong with my browser... well I gotta go to work so no time to re-write but PM me if you want the name of the forum I go to about PE (Penis Excercise) its free and all that so don't worry about that.
As for the multiples I post a bit more tomorrow maybe if I have time.... best thing though is get the pelvic floor in shape with kegels and edge towrads orgasm without cumming and ride that wave while drawing energy from the penis up the spine and into the microcosmic orbit. Deep breaths and try touching other parts of your body like the legs the lower back and chest to sensitize them to the sexual energy. Then visualize falling backwards and relaxing when you're close to cumming and try to learn to separate orgasm and ejaculation. You can stop ejaculating with a strong kegel flex if you go too far adn this will gove a "dry orgasm" but it's not the same thing, and your kegels gotta be in good shape first.....It takes a lot of practice at first, or did for me.
anwyays talk later... gotta work!
As for the multiples I post a bit more tomorrow maybe if I have time.... best thing though is get the pelvic floor in shape with kegels and edge towrads orgasm without cumming and ride that wave while drawing energy from the penis up the spine and into the microcosmic orbit. Deep breaths and try touching other parts of your body like the legs the lower back and chest to sensitize them to the sexual energy. Then visualize falling backwards and relaxing when you're close to cumming and try to learn to separate orgasm and ejaculation. You can stop ejaculating with a strong kegel flex if you go too far adn this will gove a "dry orgasm" but it's not the same thing, and your kegels gotta be in good shape first.....It takes a lot of practice at first, or did for me.
anwyays talk later... gotta work!
Duketronix- Posts : 532
Join date : 2012-06-08
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
...no injections, no apparatus just you your hands and your unit. The first thing is your junk gets WAY VEINIER and in better shape before any growth so that alone is AMAZING
Duketronix- Posts : 532
Join date : 2012-06-08
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
LawOfThelema wrote:
theres a thread on how to do this at the other forum. it involves injections. lol
I'm good lol
Duketronix wrote:...no injections, no apparatus just you your hands and your unit. The first thing is your junk gets WAY VEINIER and in better shape before any growth so that alone is AMAZING
I've noticed my unit already has massive veins on it, it's quite scary when i look at it, the main vain (cant remember it's name) is like a fire hose.
theseeker86- Posts : 518
Join date : 2011-05-05
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
SlowMoe wrote:Duketronix wrote:I have orgasms that make my whole body vibrate for up to half an hour...
How can I achieve this lol
Prostrate massage (either perineum or anus,) active imagination, maturity and restraint. With enough practice, you can experience intense orgasms (almost) every single time which then could be transferred over to sexual intercourse with a partner. Some doctors even use prostrate massage therapeutically to treat prostatitis.
4039- Posts : 780
Join date : 2010-08-22
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
keggle excercises help with stronger orgasms.
Anyways, I know what exercises to do for enlargement however it requires a lot of consistency and time. About 3 months to a year to gain 1-2 inches and the results are for keeps. I first want to fix my hair problem. Don't have the time and energy for all these things, but hopefully in the near future. It improves sex life and confidence.
Anyways, I know what exercises to do for enlargement however it requires a lot of consistency and time. About 3 months to a year to gain 1-2 inches and the results are for keeps. I first want to fix my hair problem. Don't have the time and energy for all these things, but hopefully in the near future. It improves sex life and confidence.
RisingFist- Posts : 258
Join date : 2012-08-21
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
when i fantasize about sex for a long time sometimes my left cheek and tongue goes numb, heart rate goes up high and i can get like a migraine like headache. find that really confusing wonder if there is a connection to pgd2 or maybe something else
alphadelta- Posts : 171
Join date : 2011-10-12
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
Duke, I think I know what website you are talking about
Hairbeback- Posts : 884
Join date : 2009-04-02
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
THere's a lot of interesting threads on godlikeproductions.com about baldness, this post puts it better than I can:
source: http://www.godlikeproductions.com/forum1/message2151444/pg1
This poster went on to say that the worst thing you can do is ejaculate just before going to sleep, and its much safer for your hair to do it in the morning because as you do physical activity all day it allows the blood in the scalp to flow around more.
On one level over ejaculation can definitely cause you to become deficient in minerals (especially if your diet is poor), but everytime you masturbate, you will notice how your body temp increases and how a great deal of blood rushes to the scalp, especially the temples.
This blood carries with it elevated levels of DHT. Now DHT - like testosterone - is formed from cholesterol. When too DHT molecules enter a region of the cell called the cytoplasm, the hormone blocks oxygen molecules from reaching oxygen processing organelles called mitochondria. Gradually the follicle starts to asphyxiate and it produces respiratory C02 acids. these acids lead to inflammation and thus the destruction of the follicle.
again, this issue is exacerbated by the tight skin of the galea. The tightened skin lowers oxygen delivery and cells just don't have enough ATP to metabolize excessive amounts of DHT and it builds up.
Additionally, DHT binds to androgen receptors more strongly than testosterone, and this is the reason why the hormone has a tendency to build up within the cytoplasm of cells easier.
unfortunately, it's likely that the follicle has suffered far too much inflammatory damage to regenerate, but never say never. We find alopecia totalis sufferers who have been bald for years, then suddenly regrow their hair. So may be when most DHT has been cleared from the scalp, then the follicle may begin to regenerate naturally.
source: http://www.godlikeproductions.com/forum1/message2151444/pg1
This poster went on to say that the worst thing you can do is ejaculate just before going to sleep, and its much safer for your hair to do it in the morning because as you do physical activity all day it allows the blood in the scalp to flow around more.
Espio- Posts : 736
Join date : 2008-07-29
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
That thread on godlikeproductions.com also mentions tin deficiency, which I have heard before from various sources.
ngb- Posts : 479
Join date : 2013-02-06
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
ngb wrote:That thread on godlikeproductions.com also mentions tin deficiency, which I have heard before from various sources.
What would be a good source of tin though?
theseeker86- Posts : 518
Join date : 2011-05-05
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
theseeker86 wrote:ngb wrote:That thread on godlikeproductions.com also mentions tin deficiency, which I have heard before from various sources.
What would be a good source of tin though?
Already covered.
https://immortalhair.forumotion.com/t2020-tin-and-hair-loss
Something is wrong with the search function. I searched "tin" on this site and nothing came up but I did a google search for "tin hair loss" and that thread came up.
ngb- Posts : 479
Join date : 2013-02-06
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
ngb wrote:
Already covered.
https://immortalhair.forumotion.com/t2020-tin-and-hair-loss
Something is wrong with the search function. I searched "tin" on this site and nothing came up but I did a google search for "tin hair loss" and that thread came up.
Yeah i searched tin before and didn't find anything, didn't think to use the google search.
So brewers yest is one source, does it have to have tin labeled on it to contain tin or will it just have it regardless?
http://www.iherb.com/Modern-Products-Imported-Brewer-s-Yeast-14-oz-397-g/12890?=hil335 this is the one that's on CS's regime page.
theseeker86- Posts : 518
Join date : 2011-05-05
Re: PGD2 involved in erections. Could this be the link between masturbating and baldness?
It seems like certain words don't show up in a search even though they are in the thread title. It would also be nice to be able to search the actual thread for keywords, not just the title.
ngb- Posts : 479
Join date : 2013-02-06
Page 1 of 2 • 1, 2
Similar topics
» PGD2 proven to be implicated as a cause of baldness
» Weak erections.
» Ecklonia cava erections
» OT - Achieving rock hard erections
» CS, weren't you saying bacteria is involved? Could this help?
» Weak erections.
» Ecklonia cava erections
» OT - Achieving rock hard erections
» CS, weren't you saying bacteria is involved? Could this help?
Page 1 of 2
Permissions in this forum:
You cannot reply to topics in this forum
Today at 5:05 am by Zaphod
» HMI-115: A Prolactin Receptor Antagonistic Antibody
Sun May 26, 2024 10:50 am by CausticSymmetry
» oral thrush candida
Fri May 24, 2024 1:02 pm by shaftless
» Does hair follicles taken in hair transplants donor area grow back?
Thu May 23, 2024 10:40 pm by MikeGore
» Are there any stem cell treatments that doesn't require liposuction?
Thu May 23, 2024 10:38 pm by MikeGore
» Sandalore - could it be a game changer?
Wed May 22, 2024 4:56 am by JtheDreamer
» zombie cells
Sat May 11, 2024 6:54 am by CausticSymmetry
» *The first scientific evidence in 2021 that viruses do not exist*
Tue May 07, 2024 4:18 am by CausticSymmetry
» China is at it again
Tue May 07, 2024 4:07 am by CausticSymmetry