Uridine monophosphate : any benefits for hair ?

https://examine.com/supplements/uridine/research/#PlYgaQm-interactions-with-aesthetics wrote:During the early anagen phase of hair growth, there is a marked increase in uridine accumulation into dermal papillae cells and hair germ cells relative to the dormant phase (telogen) in vitro,[100] which seems to extend to other nucleotides (such as thymidine[101] and cytidine[102]); it is thought that this is indicative of an increased RNA and DNA synthesis rate during spontaneous growth of hair cells.[100]

No studies have currently assessed whether provision of uridine is at all rate-limiting in this context, so the role of supplementing exogenous uridine to act as a substrate for DNA synthesis is not certain.

Uridine is accumulated into hair cells during the growth phase (anagen), but it is not ascertained if uridine acting as a substrate for DNA/RNA synthesis as mentioned above is at all relevant to supplementation of uridine

It has been noted that P2Y1 and P2Y2 receptors (the latter of which is a target of uridine) are expressed in hair cells undergoing anagen, with the P2Y2 receptors expressed in the living cells at the edge of the cortex/medulla and the P2Y1 receptors in the root sheath and bulb;[103] P2X5 receptors were detected in the inner and outer root sheaths and medulla while P2X7 receptors were noted to not be present.[103] The P2Y2 receptors were detected early on, as they were no longer present in the differentiated hair cuticle, and due to the roles of uridine as an agonist of this receptor causing proliferation in keratinocytes[104][105][106] it was hypothesized that uridine may stimulate hair cell differentiation.[103]

It is theoretically possible, but not yet demonstrated, that uridine can act via the P2Y2 receptor to stimulate hair cell differentiation at the beginning of the growth (anagen) phase