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Is there a consensus on wounding and or/lithium?

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Is there a consensus on wounding and or/lithium? Empty Is there a consensus on wounding and or/lithium?

Post  Paradox Sat Jan 02, 2010 4:34 am

Last year when I 'left' regrowth, many people were wounding and using derma-rollers, and there was talk of using lithium chloride and other topicals as well.

Has anyone been doing/following this at all? Meaning wounding with or without lithium? I want to try and get some temple regrowth going, and need something pretty heavy duty I think. I doubt that magnesium oil, azelaic acid, or something similar is going to be effective for that purpose.

Any threads going on this?

Thanks

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Post  TheFunkyStumpfighter Sat Jan 02, 2010 5:03 am

Ive been wondering about this myself. Last week, I dermarolled the crap out of my right temple (the first place I started losing hair almost 2 years ago now), waited a few days, and have been applying a topical of olive oil, garlic juice (fresh squeezed), aloe, and liquid deer antler velvet to the are for about a week now. Im not expecting much of anything, I just want to see if Ill see even a few scant terminals pop up.

I only used a .5mm roller, but I rolled until the area was a bleeding field of tiny puncture wounds. Im getting a 1.5mm roller for my face in a few weeks, and Ill probably try to repeat it in 6 or 7 weeks. By then, Ill have a better topical to slap on.

I suppose the question is, if someone with a fair amount of resources was to try wounding, what would be the ideal topical to use? A guy on another site used wnt3a, I wonder where they hell he got his hands on it.

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Post  thelibrarian Sat Jan 02, 2010 5:13 am

I was one of the people originally using wounding. Most of the people doing this reported a popping sensation which we assumed was fibrosis breaking up. I stopped the wounding because of concerns around microscarring. It is difficult to understand how puncturing the skin would not cause a scar.

A recent investigation lead me to this: http://www.grecohairrestoration.com/downloads/grantpaper.pdf


Greco is promoting blood platlet therapy but the research seems to indicate that wounding alone generates hair growth: microneedling initiates "stat3 dependant keratinocyte migration" I havent got a clue what this means but the researchers seem to believe that it is a good thing.

Also just read about the importance of maintaining collagen on the scalp: http://www.hairloss-research.org/UpdateRetinA9-09.html. One thing that is certain about microneedling is that it increases collagen production!

If I knew with certainty that needling did not cause micro scarring I definitely would have continued the practice. It felt great and was very stimulating to the scalp.
thelibrarian
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Post  thelibrarian Sat Jan 02, 2010 5:14 am

http://www.hairloss-research.org/UpdateRetinA9-09.html


try this instead. the one above appears to be broken
thelibrarian
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Post  kijumn Sat Jan 02, 2010 5:24 am

I personally have never been able to create enough regrowth for it to be worth it. I can get some hairs here and there but the pain and the aggravation just wasn't worth it. Interestingly, the new hairs would come in very thick.

I know everyone is hoping for Follica to be a success but I'm a skeptic based on my experiences.

BTW, LLLT should greatly help regarding increased collagen production.
kijumn
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Post  thelibrarian Sat Jan 02, 2010 5:26 am

JDP

I used acupuncture needles and would wound for an hour on friday saturday and sundays- not unpleasant at all! Did you try needles?

what about the fibrosis angle?

Also, I applied k2 again last night- I swear that bump on my forhead is almost nil- amazing!
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Post  thelibrarian Sat Jan 02, 2010 5:28 am

I guess my question is - is wounding counterproductive due to microscarring?
thelibrarian
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Post  kijumn Sat Jan 02, 2010 6:34 am

Hey thelibrarian,

I responded to this thread before I realized you asked a question on another thread, lol. To answer your question I personally am not worried about fibrosis with the "large" needles or dermarollers. I could be wrong though. You see, the 1.5 mm on up dermarollers are actually used to break up scars successfully. I have before and it helped. There is definitely a right way and a wrong way to use the large dermarollers though. The forum at essentialdayspa.com were the real pioneers in this field although they used it on their faces for wrinkles and not for hair loss. Here is an old thread with a lot of info and a lot of info in the links. http://www.hair-transplants.net/hairloss-forums/viewthread.cfm?f=1&t=23591

In short, with the large dermarollers it's used once per week for somewhere around 6 weeks and then stop. Then redo 6 months later. Also, take extra Vitamin A and E and I think some others but forget.

The small dermarollers I don't believe holds much promise for regrowth but does work for topical absorption. The problem though is the constant inflammation from the dermaroller itself. Not sure if the small dermarollers cause fibrosis but I wouldn't worry about it with the large dermarollers "when done correctly."

I haven't used the acupunture needles but have used diabetic lancets and a 1.5 mm dermaroller.
kijumn
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Post  thelibrarian Sun Jan 03, 2010 4:10 am

Hey JDP, thanks for the response - excellent links . If you have the time and inclination try the acupuncture needles! it actually feels good and is very stimulating.



BTW, any idea what the heck "stat3 dependant keratinocyte migration" means.

Also, I have been more diligent with my diet( thanks for the inspiration)- its incredible all the places they sneak crap into! I just realized that Ive been getting mass canola and soybean oil in my salad dressing. I had been avoiding soy like the plague. I felt like a fool when I checked the labels finally.
thelibrarian
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Post  kijumn Tue Jan 05, 2010 4:56 am

thelibrarian,

Just noticed the reply.

I have no idea what stat3 dependant keratinocyte migration would mean. I tried goggling stat3 but can't make heads or tails of it.
kijumn
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