Thiosulfate promotes hair growth in mouse model

https://www.tandfonline.com/doi/abs/10.1080/09168451.2018.1518705?journalCode=tbbb20

Thiosulfate promotes hair growth in mouse model
Motoko Maekawa, Tetsuo Ohnishi, Shabeesh Balan, Yasuko Hisano, Yayoi Nozaki, Hisako Ohba, show all
Received 13 Jul 2018, Accepted 23 Aug 2018, Published online: 10 Sep 2018
Download citation https://doi.org/10.1080/09168451.2018.1518705


The present study describes the hair growth-promoting effects of sodium thiosulfate (STS), a widely used compound, in mice. STS accelerated hair growth in the “telogen model”, suggesting that it stimulates telogen hair follicles to reenter the anagen phase of hair growth. In the same model, STS potentiated hair growth in an additive manner with minoxidil (MXD), a drug used for the treatment of androgenic alopecia. Furthermore, in the “anagen model”, STS promoted hair growth, probably by promoting hair follicle proliferation. Since STS elevated the skin surface temperature, its hair growth-promoting activity may be partly due to vasorelaxation, similar to MXD. In addition, STS is known to generate a gaseous mediator, H2S, which has vasorelaxation and anti-inflammatory/anti-oxidative stress activities. Therefore, STS and/or provisionally its metabolite, H2S, may aid the hair growth process. Collectively, these results suggest that salts of thiosulfate may represent a novel and beneficial remedy for hair loss.


We found the hair growth-promoting effects of sodium thiosulfate (STS) in mice. STS may represent a beneficial remedy for hair loss.

Thx for posting!
Also great studies on this reversing calcification!
I just ordered some

bocor wrote:Thx for posting!
Also great studies on this reversing calcification!
I just ordered some

Best of success on this. Since it's only been examined in mice (topically), hopefully it will work.