Stimulation of Hair Growth by Small Molecules that Activate Autophagy.

Cell Rep. 2019 Jun 18;27(12):3413-3421.e3. doi: 10.1016/j.celrep.2019.05.070.
Stimulation of Hair Growth by Small Molecules that Activate Autophagy.
Chai M1, Jiang M2, Vergnes L3, Fu X2, de Barros SC4, Doan NB4, Huang W2, Chu J2, Jiao J2, Herschman H5, Crooks GM6, Reue K7, Huang J8.

Hair plays important roles, ranging from the conservation of body heat to the preservation of psychological well-being. Hair loss or alopecia affects millions worldwide, but methods that can be used to regrow hair are lacking. We report that quiescent (telogen) hair follicles can be stimulated to initiate anagen and hair growth by small molecules that activate autophagy, including the metabolites α-ketoglutarate (α-KG) and α-ketobutyrate (α-KB), and the prescription drugs rapamycin and metformin, which impinge on mTOR and AMPK signaling. Stimulation of hair growth by these agents is blocked by specific autophagy inhibitors, suggesting a mechanistic link between autophagy and hair regeneration. Consistently, increased autophagy is detected upon anagen entry during the natural hair follicle cycle, and oral α-KB prevents hair loss in aged mice. Our finding that anagen can be pharmacologically activated in telogen skin when natural anagen-inducing signal(s) are absent has implications for the treatment of hair loss patients.

They should do a study on diabetic men taking metformin to see how many still have lots of hair.

Hi immortalhaur!! I dont know what happenned to this forum but i have no access to old post! Like those from prague, you, the one with rife machine.. i dont remember his name xD

But i wanted to tell you this!

I reversed my hairloss with those

Tetrasodium edta (chelate realy well calcium bumps or calcium oxalate formation)
H2o2 (kill bad things)
Borax(kill fungus like) topical internal
Liver powder (all my mineral i need)
Green clay topical/internal
Lavender essential oil topical also
Tea tree essential oil topical also
Khella essential oil(kill well nanobacteria) topical internal
Iodine
Sodium thiosulfate
Epson salt
Baking soda
Granulated lecithin
Topical colloidal silver+h2o2

took me arround 6 month of cleaning!

And i avoid sugar, vegetable oil and try to avoid bread/pasta as much as i can (damm bromine!!!!!)

Mapag wrote:Hi immortalhaur!! I dont know what happenned to this forum but i have no access to old post! Like those from prague, you, the one with rife machine.. i dont remember his name xD

But i wanted to tell you this!

I reversed my hairloss with those

Tetrasodium edta (chelate realy well calcium bumps or calcium oxalate formation)
H2o2 (kill bad things)
Borax(kill fungus like) topical internal
Liver powder (all my mineral i need)
Green clay topical/internal
Lavender essential oil topical also
Tea tree essential oil topical also
Khella essential oil(kill well nanobacteria) topical internal
Iodine
Sodium thiosulfate
Epson salt
Baking soda
Granulated lecithin
Topical colloidal silver+h2o2

took me arround 6 month of cleaning!

Interesting, what were the dosages that you used for each internal supplement? I've read positive things about Sodium Thiosulfate for treating calcification but I have no clue on how to dose it properly.

Mapag wrote:Hi immortalhaur!! I dont know what happenned to this forum but i have no access to old post! Like those from prague, you, the one with rife machine.. i dont remember his name xD

But i wanted to tell you this!

I reversed my hairloss with those

Tetrasodium edta (chelate realy well calcium bumps or calcium oxalate formation)
H2o2 (kill bad things)
Borax(kill fungus like) topical internal
Liver powder (all my mineral i need)
Green clay topical/internal
Lavender essential oil topical also
Tea tree essential oil topical also
Khella essential oil(kill well nanobacteria) topical internal
Iodine
Sodium thiosulfate
Epson salt
Baking soda
Granulated lecithin
Topical colloidal silver+h2o2

took me arround 6 month of cleaning!

Any chance you could send before afters?


This autophagy process seems really legit. Could we promote it by taking olive leaf extract supplements?

GiantofDawn wrote:This autophagy process seems really legit. Could we promote it by taking olive leaf extract supplements?

Fasting is one way to trigger autophagy.