Search
Check Out Our Sponsors
Latest topics
Folliculitis decalvans: a multicentre review of 82 patients
2 posters
Page 1 of 1
Folliculitis decalvans: a multicentre review of 82 patients
J Eur Acad Dermatol Venereol. 2015 Feb 12. doi: 10.1111/jdv.12993. [Epub ahead of print]
Folliculitis decalvans: a multicentre review of 82 patients.
Vañó-Galván S1, Molina-Ruiz AM, Fernández-Crehuet P, Rodrigues-Barata AR, Arias-Santiago S, Serrano-Falcón C, Martorell-Calatayud A, Barco D, Pérez B, Serrano S, Requena L, Grimalt R, Paoli J, Jaén P, Camacho FM.
BACKGROUND:
Folliculitis decalvans (FD) is a rare neutrophilic scarring alopecia that represents a therapeutic challenge for dermatologists.
OBJECTIVE:
To describe the epidemiology, comorbidities, clinical presentation, diagnostic findings and therapeutic options in a large series of patients with FD.
METHODS:
This retrospective multicentre review includes patients diagnosed with FD based on clinical and histopathologic findings. The clinical severity was determined by the maximum diameter of the largest alopecic patch (slight: <2 cm, moderate: 2-4.99 cm, severe: 5 cm or more). Response to therapy was assessed as improvement, worsening or stabilization depending on the clinical symptoms (pruritus and trichodynia), inflammatory signs (erythema, pustules and crusts) and the extension of the alopecic patch.
RESULTS:
Overall, 82 patients (52 males and 30 females) with a mean age of 35 years were included. No significant comorbidities were present. A family history was present in three males. Severe FD was observed in 17 patients (21%). The independent factors associated with severe FD after multivariate analysis were: onset of FD before 25 years of age and presence of pustules. Oral antibiotics (tetracyclines and the combination of clindamycin and rifampicin) improved 90% and 100% of the patients, with a mean duration of response of 4.6 and 7.2 months respectively.
CONCLUSIONS:
The onset of FD before 25 years of age and the presence of pustules within the alopecic patch were associated with severe FD. Tetracyclines and the combination of clindamycin and rifampicin were the most useful treatments.
Folliculitis decalvans: a multicentre review of 82 patients.
Vañó-Galván S1, Molina-Ruiz AM, Fernández-Crehuet P, Rodrigues-Barata AR, Arias-Santiago S, Serrano-Falcón C, Martorell-Calatayud A, Barco D, Pérez B, Serrano S, Requena L, Grimalt R, Paoli J, Jaén P, Camacho FM.
BACKGROUND:
Folliculitis decalvans (FD) is a rare neutrophilic scarring alopecia that represents a therapeutic challenge for dermatologists.
OBJECTIVE:
To describe the epidemiology, comorbidities, clinical presentation, diagnostic findings and therapeutic options in a large series of patients with FD.
METHODS:
This retrospective multicentre review includes patients diagnosed with FD based on clinical and histopathologic findings. The clinical severity was determined by the maximum diameter of the largest alopecic patch (slight: <2 cm, moderate: 2-4.99 cm, severe: 5 cm or more). Response to therapy was assessed as improvement, worsening or stabilization depending on the clinical symptoms (pruritus and trichodynia), inflammatory signs (erythema, pustules and crusts) and the extension of the alopecic patch.
RESULTS:
Overall, 82 patients (52 males and 30 females) with a mean age of 35 years were included. No significant comorbidities were present. A family history was present in three males. Severe FD was observed in 17 patients (21%). The independent factors associated with severe FD after multivariate analysis were: onset of FD before 25 years of age and presence of pustules. Oral antibiotics (tetracyclines and the combination of clindamycin and rifampicin) improved 90% and 100% of the patients, with a mean duration of response of 4.6 and 7.2 months respectively.
CONCLUSIONS:
The onset of FD before 25 years of age and the presence of pustules within the alopecic patch were associated with severe FD. Tetracyclines and the combination of clindamycin and rifampicin were the most useful treatments.
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Re: Folliculitis decalvans: a multicentre review of 82 patients
Thanks CS
I have pustules in the scalp, some irritatingly sore.
Have had these for over 3 years now.
Any suggestions?
I have pustules in the scalp, some irritatingly sore.
Have had these for over 3 years now.
Any suggestions?
Live forever- Posts : 318
Join date : 2013-04-25
Location : UK
Re: Folliculitis decalvans: a multicentre review of 82 patients
[quote="Live forever"]Thanks CS
I have pustules in the scalp, some irritatingly sore.
Have had these for over 3 years now.
Any suggestions?[/quote
The only natural treatment for this that I know of is laser treatment.
http://www.ncbi.nlm.nih.gov/pubmed/23875611
I have pustules in the scalp, some irritatingly sore.
Have had these for over 3 years now.
Any suggestions?[/quote
The only natural treatment for this that I know of is laser treatment.
http://www.ncbi.nlm.nih.gov/pubmed/23875611
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Similar topics
» Intravenous human immunoglobulin for treatment of folliculitis decalvans
» Androgenetic Alopecia in the Pediatric Population: A retrospective review of 57 patients.
» Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review
» Coconut, Castor, and Argan Oil for Hair in Skin of Color Patients: A Systematic Review
» Folliculitis
» Androgenetic Alopecia in the Pediatric Population: A retrospective review of 57 patients.
» Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review
» Coconut, Castor, and Argan Oil for Hair in Skin of Color Patients: A Systematic Review
» Folliculitis
Page 1 of 1
Permissions in this forum:
You cannot reply to topics in this forum
|
|
Today at 8:05 am by CausticSymmetry
» zombie cells
Sat May 11, 2024 6:54 am by CausticSymmetry
» Sandalore - could it be a game changer?
Wed May 08, 2024 9:45 pm by MikeGore
» *The first scientific evidence in 2021 that viruses do not exist*
Tue May 07, 2024 4:18 am by CausticSymmetry
» China is at it again
Tue May 07, 2024 4:07 am by CausticSymmetry
» Ways to increase adult stem cells
Mon May 06, 2024 5:40 pm by el_llama
» pentadecanoic acid
Sun May 05, 2024 10:56 am by CausticSymmetry
» Exosome Theory and Herpes
Fri May 03, 2024 3:25 am by CausticSymmetry
» Road to recovery - my own log of everything I'm currently trying for HL
Tue Apr 30, 2024 1:55 pm by JtheDreamer