Acne Tarda and Male-Pattern Baldness Unmasking Primary Ovarian Insufficiency: A Case and Review

Dermatology. 2014 Sep 9. [Epub ahead of print]
Acne Tarda and Male-Pattern Baldness Unmasking Primary Ovarian Insufficiency: A Case and Review.
Zouboulis CC1, Achenbach A, Makrantonaki E.

A 30-year-old woman presented with recurrent acne lesions and progressing male-pattern baldness. Furthermore, she reported amenorrhea, weight loss, mucosal xerosis and dyspareunia since discontinuation of hormonal contraception 6 months earlier in order to conceive. Acne tarda and androgenetic alopecia of female pattern were diagnosed. Hormonal and immunologic serological and ultrasound examinations revealed an autoimmune hypergonadotropic primary ovarian insufficiency (POI) with no ovarian cysts but ovarian fibrosis with marked reduced follicle pool. Immediate ovarian stimulation and in vitro fertilization led to pregnancy and the patient gave birth to a healthy child. Though presenting with clinical findings similar to menopause, 50% of patients with POI exhibit varying and unpredictable ovarian function, and only 5-10% are able to accomplish pregnancy. Genetic disorders affect the X chromosome. In 14-30% of cases POI has been associated with autoimmunity. POI may occur after discontinuation of hormonal contraception, like in our case.

Very interesting. I cant believe theres not more on the relationship with acne/mpb.

Areas that hair have miniaturized on my scalp are areas that had sore, red and yellow topped spots.
They come and go, and also affect the sides and back.
Ive had a huge spot about 1cm back from the middle of my hairline. This was there for about 6 months, and subsequently ive thinned exactly around that area.

Its a very irritating thing that im trying to get under control.

Live forever - There's lots of studies on the subject in general, although most of the research has been posted years ago on it. Here's one you might find interesting. Even though it is on women, PCOS is substantially equivalent of MPB in men.

Gynecol Endocrinol. 2009 Aug;25( 8 ):508-13. doi: 10.1080/09513590903015544.
Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome.
Zacchè MM1, Caputo L, Filippis S, Zacchè G, Dindelli M, Ferrari A.

BACKGROUND:
Polycystic ovary syndrome (PCOS) is the most common endocrine cause of hirsutism, acne and pattern alopecia, often characterised by ovulation disorders (usually manifested as oligo- or amenorrhea). In addition, 30-40% of women with PCOS have impaired glucose tolerance, and a defect in the insulin signalling pathway seems to be implicated in the pathogenesis of insulin resistance. For this reason, insulin-lowering medications represent novel approach in women with PCOS. The aim of this study was to evaluate the effects of myo-inositol (MYO), an isoform of inositol, belonging to the vitamin B complex, in the treatment of cutaneous disorders like hirsutism and acne.
METHODS:
Fifty patients with PCOS were enrolled in the study. BMI, LH, FSH, insulin, HOMA index, androstenedione, testosterone, free testosterone, hirsutism and acne were evaluated at the baseline and after receiving MYO therapy for 6 months.
RESULTS:
After 3 months of MYO administration, plasma LH, testosterone, free testosterone, insulin and HOMA index resulted significantly reduced; no significant changes were observed in plasma FSH and androstenedione levels. Both hirsutism and acne decreased after 6 months of therapy.
DISCUSSION:
MYO administration is a simple and safe treatment that ameliorates the metabolic profile of patients with PCOS, reducing hirsutism and acne.

I see.
So long term use of brewers yeast would be beneficial do you think?
Also, is there a better time to take BY to optimize intake?

Live forever wrote:I see.
So long term use of brewers yeast would be beneficial do you think?
Also, is there a better time to take BY to optimize intake?

Yes, brewer's yeast is a source of tin (suspected to grow hair in humans, it does in animals), plus the natural source of B-vitamins.