my hairline is getting crazy!

Papain, the proteolytic enzyme from the fruit of carica papaya, is a potent digestant of nonviable protein matter but is harmless to viable tissue. It is active over a pH range of 3 to 12. Papain is relatively ineffective when used alone as a debriding agent and requires the presence of activators to stimulate its digestive potency. In ACCUZYME, papain is combined with urea, a denaturant of proteins, to bring about two supplemental chemical actions: (1) to expose by solvent action the activators of papain, and (2) to denature the nonviable protein matter in lesions and thereby render it more susceptible to enzymatic digestion. Pharmacologic studies have shown that the combination of papain and urea result in twice as much digestive activity as papain alone.

Papain-Urea (10%/10%) Salve / Ointment by Bianca Rosa

Ingredients: Beeswax, Glycerin (Vegetable Source), Papain (Papaya Enzyme), Urea, Benzoin (Preservative), Jojoba Oil, Lanette Wax (Emulsifier)


Description

Helps Restore Balance to Healthy Skin Providing Soothing Topical Relief to Minor Skin Burns or Abrasions - For Your Heels, Hands, Fingers, Elbows, Knees and Feet - Fragrance-Free!

Bianca Rosa Papain-Urea (10%/10%) Salve / Ointment helps absorb and retain moisture into the dry areas of your skin such as your elbows, knees, heels, hands and fingers. Combined with papain, urea, and jojoba oil, Bianca Rosa Papain-Urea (10%/10%) Salve / Ointment helps to break down dead or damaged tissue that may result from minor skin abrasions, burns, irritations, or sores, leaving behind soft, noursihed and healthy skin!

A non-greasy, non-staining formula, Bianca Rosa Urea Papain-Urea (10%/10%) Salve / Ointment does not just cover your skin like other skin-care products. Use it to facilitate the healing of minor cuts, scrapes, or burns and to assist and enhance the penetration and retention of moisture to your skin.

Directions

Apply Bianca Rosa Papain-Urea (10%/10%) Salve / Ointment morning and evenings, or as directed by a health care practitioner. On a moist cotton wool pad or with the fingertips, apply to the desired area of the body. Massage onto thoroughly cleansed skin with a gentle circular motion.

Whip wrote:Hey Gibson, maybe you can exchange that papain for something else. I'm sure that natural estrogens help hairloss a little, but overtime the sides are too great. I know for myself for overall health, I'd rather err on the side of T than E.

Try a garlic clove 1x a day and see if that helps. I cut a clove up into four pieces, make sure there are no sharp/pointy edges and swallow with room temp water. Cold water is a bad idea because the pieces can be large.

Do you notice hair texture changes from the different internals you are taking? I'm currently looking at blackstrap molasses and black sesame seed powder/tea to add to my regimen. There is a sulphured version of blackstrap, so maybe I wouldn't have to take MSM if I get sulphur from that, although, it's in the garlic also.

Gibson wrote:
One thing that also makes me a skeptic about papain is that people have been using peels and retonic acid for years. Seems like there may be some benefit at the cost of cosmetically frying your hair. The unclogging approach has been around a while and doesn't seem to yield beautiful hair. De-calcification on the other hand seems to work wonders (mag oil).

hapyman wrote:

Gibson wrote:
One thing that also makes me a skeptic about papain is that people have been using peels and retonic acid for years. Seems like there may be some benefit at the cost of cosmetically frying your hair. The unclogging approach has been around a while and doesn't seem to yield beautiful hair. De-calcification on the other hand seems to work wonders (mag oil).

Except papain just doesn't "unclog" the follicles. The interesting thing about papain is its propensity to breakdown dead tissue or scarring while leaving healthy tissue intact. So papain should in theory help break down fibrosis while allowing healthy collagen to be laid down behind it. If you already have your hairloss under control or close to it, papain could be used to reverse some of the damage that has been laid. This is the biggest hurdle in getting good regrowth and currently JDP is taking a similar route, except more internal, with the proteolytic enzymes and pauling protocol. The combination of topical papain and hylauronic acid is interesting as well as possibly adding topical lysine and vitamin C.

JHarsh80 wrote:Have you eve stopped to think about waht 'to vain' means? To you it is your physique ... to some of of us it is MPB! Some of us will stop at nothing to reverse this auttoimunity that we call AA (androgenetic alopecia). The fact that you place more importance on your physique points to the fact that this is not your number one priority.

Compositions and method for promoting the growth of human hair

TECHNICAL FIELD

This invention relates generally to compositions and methods directed at promoting the growth of hair in men and women and other mammals. Specifically, this invention is directed at compositions comprising monoethanolamine salts of thioglycolic, salicylic, lactic and glycolic acids in combination with an enzyme, preferably papain, with an oxidizing agent, and their methods of use to induce hair growth in the scalp of humans and other mammals.

BACKGROUND OF THE INVENTION

The average male or female scalp is endowed with between 100,000 and 150,000 hair follicles from which human hairs are generated. Generally, adult human hair can be divided into two categories, “vellous” and “terminal” hair. Vellous hair is comprised of very thin short hairs, only a centimeter or two long, that contain little or no pigment. The follicles that produce vellous hair do not have oil glands (often called sebaceous glands), and never produce any other kind of hair. Terminal hair is comprised of the long hairs that grow on the head and in many people on the body, arms and legs too. They are produced by follicles with sebaceous glands. In people who have inherited a tendency to baldness the hairs in these follicles gradually become thinner and shorter until they look like vellous hairs.

The human hair growth cycle is essentially composed of three stages which repeats indefinitely in healthy follicles. The three known growth stages which have been identified are: (a) the anagen stage, during which the hair grows, (b) the katagen stage, during which the hair follicle prepares for the next phase, the telogen, and the previously growing hair is converted into a resting hair or club hair and (c) the telogen, which is the resting phase during which hair growth ceases completely. Using a mechanism, not yet fully understood, at some point at the end of the cycle, telogenic follicles commence forming new anagens, causing new hair to grow and existing hair to fall out. This growth cycle repeats itself unchanged during the life of the follicle and is essentially identical for vellous or terminal hair-producing follicles.

It has been determined through observation and experimentation that in order for abundant hair growth to occur, healthy follicles and a good supply for it of all necessary nutrients are required. Unhealthy follicles, such as caused by disease or stress, or improper nutrition can thus result in loss of hair. Hair loss brought about by these factors, however, is usually temporary and can be reversed by eliminating the unhealthy conditions. Such reversible conditions, generally of unknown origin, should not be confused with the more chronic conditions which cause irreversible hair loss by replacing terminal hair with vellous hair and eventually no hair.

The exact pathogenic or genetic mechanism that triggers the shift in certain follicles from producing terminal to vellous, and eventually to a complete absence of, hair, is the subject of much debate. Suffice it to say that there is no consensus among those skilled in the art as to the causes of hair loss in men and women. As a result, numerous attempts have been made to provide methods and/or compositions which effectively, and without adverse consequences, can prevent or reverse the seemingly permanent shift from terminal to vellous hair-producing follicles in certain persons.

However, none of these attempts have proven satisfactory from the standpoint of efficacy, convenience, safety or cost. Accordingly, there is a present need for a convenient, inexpensive, safe and efficient compound to treat persons suffering from hair loss conditions, such as alopecia.

SUMMARY OF THE INVENTION

The subject invention resolves the above-described needs and problems by providing an easy to produce, inexpensive and effective compositions, and method of using same, for the treatment of premature hair loss in adult men and women.

The compositions of the present invention comprises two separate products. The first product is keratin reducing compound comprising a combination of salts, preferably monoethanolamine salts, of thioglycolic, salicylic, lactic and glycolic acids with an enzyme, preferably papain. The second product is an oxidizing compound which restores keratin in hair to its state before application of the first product.

In its preferred embodiment, the present invention relies on the unexpected and beneficial reaction between four salts, an enzyme and sunlight to eliminate the obstacles that block hair growth in the human scalp. It is believed that ultraviolet-B (“UV-B”) radiation present in sunlight augments and stimulates the growth of epithelial cells and sebaceous glands which surround human hair follicles resulting in stimulation of the dermal papilla and, consequently, in hair growth.

It is commonly believed that alopecia is caused by a pathological dystrophy of hair follicles which eventually results in their eventual death and replacement by connective fatty tissue. What is required to reverse this pathology are chemical compounds that eliminate excess fatty deposits found in the follicle and surrounding areas of the epidermis.

The four salts employed in the invention are:

Monoethanolamine thioglycolate,

Monoethanolamine salicylate,

Monoethanolamine lactate, and

Monoethanolamine glycolate.

The enzyme utilized in the preferred embodiment is papain. It is believed that the effect of eliminating the hair-loss inducing connective fatty tissue is achieved by the monoethanolamine salts through the elimination of disulfuric bonds present in the keratin amino-acid cystine. Keratin is the essential component of hair, consequently, of the hair follicle root. Cystine is broken down by the monoethanolamine salts into cysteine, which is the reduced state of keratin. After the damaging cells are removed, through a process of oxidation, the disulfuric bonds are reestablished, returning the hair keratin to its original state. The detergent characteristics of monoethanolamine help carry the removed cells safely away from the follicle which in turn stimulates growth of the follicle. The papain enzyme imparts elasticity over the keratin and skin tissues to ease the elimination of pathogenic cells.

Having re-activated the previously dormant hair follicles, and provided said follicles are located in areas where blood circulation is sufficient to deliver required nutrients, hair growth is immediately stimulated and anagenic hair can be seen to develop within a matter of hours after treatment.

The compositions of the present invention have been observed to induce significant long-term hair growth in areas of scalp which were previously devoid, or nearly devoid, of terminal hairs. Such effect has been observed after treatment of the scalp for periods of less than 60 minutes, and with such treatments occurring once every 3 to 12 months. These beneficial results have been achieved without any significant adverse health effects.

Accordingly, it is an object of the present invention to provide a convenient, inexpensive, safe and efficient compound to treat persons suffering from hair loss conditions, such as alopecia.

These and other objects, features, and advantages of the present invention may be more clearly understood and appreciated from a review of ensuing detailed description of the preferred and alternate embodiments and by reference to the accompanying drawings and claims.

Technical portion skipped here

III. Method of Use

The preferred method of use is different for men and women due to physiological reasons which are not well understood. It has been observed that women generally require less treatment than men.

In a typical treatment, the Monoethanolamine Salt Product is applied topically to the roots of a cleaned scalp using a plastic applicator that allows sufficient precision for this task. The Monoethanolamine Salt Product is left on the scalp for approximately one (1) hour (for men) or 45 minutes (for women) and the scalp is then thoroughly washed with warm water and massaged until none of the product can be felt on the scalp.

Next, the Oxidizing Agent is topically applied to the scalp in the same fashion. The Oxidizing Agent should be allowed to remain on the scalp for 30 minutes or longer (regardless of whether the patient is male or female) and then the scalp should be thoroughly washed with warm water and massaged until none of the agent can be felt on the scalp.

Treatment sessions should be spaced at least 3 months apart. As previously stated, it has been observed that women generally require less treatment than men. Accordingly, the treatment sessions for women can be spaced apart as long as 12 months.

It has been observed through experimentation that in addition to the hair growth effects described above, the compositions of the present invention also have cosmetic effects. Particularly, the compositions of the present invention give hair a thicker, healthier appearance and appear to induce regeneration of the scalp tissue. Moreover, scalp conditions such as dandruff, seborrhea and psoriasis show marked improvement and reduced symptoms as a result of use of the disclosed compounds.

Finally, it should also be pointed out that the above effects of the disclosed invention, including the hair growth and cosmetic effects, have been demonstrated to occur not only in humans but also in many other mammals.

Accordingly, it will be understood that the preferred embodiments of the invention have been disclosed by way of example and that other modifications and alterations may occur to those skilled in the art without departing from the scope and spirit of the appended claims.