Association between androgenetic alopecia and periodontitis

J Periodontal Res. 2023 Oct;58(5):1105-1111. doi: 10.1111/jre.13175. Epub 2023 Aug 12.
Association between androgenetic alopecia and periodontitis
Yerda Özkan Karasu 1 2, Recep Orbak 2, Kamber Kaşalı 3, Ezel Berker 4, Alpdogan Kantarci 1 5

Aim: Androgenic alopecia (AGA) is men's most common form of hair loss. It is affected by changes in the expression and activity of 5αR and the metabolism of testosterone and DHT. There is an association between AGA and systemic inflammatory diseases. We hypothesized that there is an association between AGA and periodontal disease, as inflamed gingiva and periodontal fibroblasts have been shown to express more 5αR. Thus, this study aimed to evaluate the relationship between periodontal disease and AGA and the potential effect of aging on this association.

Materials and methods: Out of a cohort of 1088 individuals, 385 white males aged 25-65 with similar socioeconomic levels and without systemic disease were included. Periodontitis was defined using NHANES data. AGA was evaluated using the Norwood-Hamilton scale. The relationship between AGA, periodontal disease severity, and age was assessed.

Results: There was a correlation between age and baldness (r = .421, p < .001). There was a significant correlation between AGA and periodontal disease in younger patients aged 25-34 and 35-44. (p < .042 and p < .036, respectively). There was no significant correlation between AGA and periodontal disease in the 45-54 and 55-65 age groups (p > .05).

Conclusion: There may be a relationship between periodontal disease and AGA in the 25-44 age range, suggesting that this association starts at an early age in adulthood.

Keywords: androgenetic alopecia; periodontal disease.

There was someone on here who reported his MPB stopped immediately after getting some dental work done.

https://immortalhair.forumotion.com/t9616-dental-work-stopped-my-hair-loss

manofmanytrades wrote:Thought I'd share my experience with everyone...
I managed to get my hairloss under control many months ago using suggestions posted on here...diet, supplements, parasite elimination, chelation, and around an hour of manual methods every day.  I'd still have ups and downs, depending on different factors...but even on my best days id end up with 4 or 5 good hairs on my hand when showering.

A little over two months ago I went to see doc about other issues, and he had requested a panoramic dental xray to check for hidden infections.  He looked at it and recommended I see a biological dentist to have my old wisdom tooth extraction sites re-opened.  He showed me on the xray a very very faint white outline, nobody else ever even noticed it.  Went to his recommended dentist, the guy spent an hour digging out bacteria cysts from my jawbone... filled it in with some special compound with vitamin k2 after disinfecting with ozone.  He put it all in a baggy to send off for biopsy-close to a quarter teaspoon of rotten tissue and bacteria.  Ever since then my hair loss is stopped in its tracks-literally lose no hair in the shower ever, and ive cut back on manual methods to 20 minutes every couple days, slacked up on my diet quite a bit too.  The dentist believed the other side probably is infected as well, so Ill go back at some point to have that opened too.  

Point is, even if you don't have amalgams or a lot of cavities it could be as simple as old wisdom tooth site infection.  All those toxins get released into the head and lymph drainage cant keep up.  Just wanted to share that story with everyone on here...

Personally my health problems, including hair loss, started around the time that I noticed a significant increase in tartar buildup. In retrospect, I suspect this may be related to weight gain at the time. I was trying to gain weight, but I gained significant fat in addition to muscle.

CS, what do you think about a baking soda and hydrogen peroxide combo to eliminate tartar? Many people claim that this is very effective, but others say that it can erode enamel and cause gum inflammation.

https://www.youtube.com/watch?v=0ktNhvkmB00

Also do you have any advice on removing subgingival tartar? I think swishing with baking soda and H2O2, combined with gum massage, might work.

It's funny you posted this now. I am back on this forum for the first time in years, been here on and off for around 15 years at this point. I managed to stabilize my hair loss, maybe with some very mild regrowth, but nothing beyond that. I feel very close to a breakthrough in my health, related to oral health, for the following reason.

A few weeks ago I started having almost panic attack levels of anxiety. I was scheduled to see a dentist for routine cleaning, but for various reasons the cleaning did not happen. I went home that day feeling almost psychotic, and like I just needed to clean off that tartar. I eventually said fuck it and started pulling the tartar off with my fingernails. Somehow I managed to remove most of it, and within a few hours my mental state had improved dramatically. This was a week ago and I still feel mentally so much better.

I still have some anxiety, but I think my health in general will improve tremendously once I figure out oral health. This may simply be a matter of fixing my overall health, from which good oral health will follow naturally. Or maybe I need to address oral health directly. To some extent it may be hereditary, my father has terrible oral health despite decades of good oral hygiene practices.

Tartar build-up itself is not necessarily the culprit. However oral hygiene has mostly to do with digestion, which is primarily driven by diet.

In other words, if hair growth is being challenged, it would be first a good idea to have a 3-D cone X-ray, to determine pathology in specific teeth, which are numbered on a dental meridian chart.

So if "hot spots" show up, those teeth or sockets, could be culprits.

However, if we assume there is nothing to clean, and the oral bacteria and GI-tract are not chronic, only in the initial stages--meaning no deep or infections that have taken hold, the best way to clear up, let's say tartar is to not provoke the glycerol-fatty acid cycle (Randle Cycle). Also high-stress can impact this as well.

I remember when I was between the ages of 24 and 28, my oral health was a disaster. Those were the days when my 'education' in all forms were based on unproven hypothesis, promoted as "truths."

My hair took a significant hit and during that time, my breath was awful.....How did I know that? My GF told me, I had no clue. Anyway, lots of astringents, "medically strong" to kill off all the 'bad bacteria.' so I thought, well that was all bad advice I tried.

Just on the tartar idea alone, buying some Xylitol gum or Xylitol itself can reduce it and it will not ruin the bacteria balance. Mouthwashes or astringents on the other hand will not only ruin oral bacteria balance, it will also cause the libido to sink.

This is just a small part, as greater context is needed for more details.