Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia

Skin Pharmacol Physiol 2020;33:153–169
https://doi.org/10.1159/000508228

Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review
Völker J.M. · Koch N. · Becker M. · Klenk A.

Caffeine, particularly after ingestion, is well known to exert various pharmacological effects. A growing body of evidence implicates the ingestion of caffeine with beneficial effects on several diseases. The easy penetration of caffeine across the skin barrier and into human skin makes caffeine an ideal compound for topical application. Hair loss is known to negatively affect the quality of life and predispose to depression and anxiety. Androgenetic alopecia (AGA) is the most common type of hair loss in both men and women. To date, only few approved drug-based treatments for AGA exist, and these are inevitably associated with side effects. Therefore, the development of topical treatments based on well-tolerated natural ingredients such as caffeine to alleviate hair loss may provide a much-needed alternative to drug-based approaches.

2020 S. Karger AG, Basel

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https://www.karger.com/Article/FullText/508228

This is the easiest and cheapest thing to test. You can make really strong coffee or buy caffeine pills and dissolve them and rub it on your head. I'm sure a lot of people tried this. Never heard of anything positive.

shaftless wrote:This is the easiest and cheapest thing to test. You can make really strong coffee or buy caffeine pills and dissolve them and rub it on your head. I'm sure a lot of people tried this. Never heard of anything positive.

I'm not a fan of the idea (yes, I've tried it), but I posted this anyway.

The fastest way to get a caffeine-induced headache.

CS, Is there a dosage recommendation that bypasses the problem, yet benefit can be achieved?

Zaphod wrote:The fastest way to get a caffeine-induced headache.

CS, Is there a dosage recommendation that bypasses the problem, yet benefit can be achieved?

The issue that I had at least, it's a bit like drinking coffee and then stopping. If you forgot to apply the dose, then a headache.

It would seem if you can get the dose within the perfect threshold, based on research there's an ideal amount.

Here are results of one of the studies cited using a caffeine dosed shampoo:

http://www.iscd.it/files/Use-of-a-Cosmetic-Caffeine-Lotion-in-the-Treatment-of-Male-Androgenetic-Alopecia.pdf