Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

Dermatol Surg. 2011 Aug 24. doi: 10.1111/j.1524-4725.2011.02123.x.
Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth.
Takikawa M, Nakamura S, Nakamura S, Ishirara M, Kishimoto S, Sasaki K, Yanagibayashi S, Azuma R, Yamamoto N, Kiyosawa T.

Departments of *Plastic Surgery and †Surgery and ‡Research Institute, National Defense Medical College, Tokorozawa, Saitama, Japan; §Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan.

BACKGROUND Treatments for alopecia are in high demand, but not all are safe and reliable. Dalteparin and protamine microparticles (D/P MPs) can effectively carry growth factors (GFs) in platelet-rich plasma (PRP). OBJECTIVE To identify the effects of PRP-containing D/P MPs (PRP&D/P MPs) on hair growth. METHODS & MATERIALS Participants were 26 volunteers with thin hair who received five local treatments of 3 mL of PRP&D/P MPs (13 participants) or PRP and saline (control, 13 participants) at 2- to 3-week intervals and were evaluated for 12 weeks. Injected areas comprised frontal or parietal sites with lanugo-like hair. Experimental and control areas were photographed. Consenting participants underwent biopsies for histologic examination. RESULTS D/P MPs bind to various GFs contained in PRP. Significant differences were seen in hair cross-section but not in hair numbers in PRP and PRP&D/P MP injections. The addition of D/P MPs to PRP resulted in significant stimulation in hair cross-section. Microscopic findings showed thickened epithelium, proliferation of collagen fibers and fibroblasts, and increased vessels around follicles. CONCLUSION PRP&D/P MPs and PRP facilitated hair growth but D/P MPs provided additional hair growth. The authors have indicated no significant interest with commercial supporters.

Well can i know the major difference in opting for such kind of treatments or rather preferring for surgeries of Hair Transplant.

any idea if this prp+acell enhanced w/ Dalteparin and protamine microparticles (D/P MPs) treatment is already available at a company like recoverup & co which claims great results w/ their prp+acell like treatment, even if they in fact try to sell you surgery (fu) more than just prp injection, making clear than just prp is not enough...

i wonder if just dermarolling dalterparin & protamine solution would do the trick. both seem available as drug easily.