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Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
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Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
Little More Than in Many 'Multis' Can Trigger Subclinical Hypothyroidism, Less Selenium (25% of the RDA) Cuts 13% Body Fat in 10 Weeks
"That "only" 279 mcg/day which is still 30% less than the upper intake level of 400 mcg/day and far away from the toxic range, but only slightly more than what you'll find in many "high potency multi-vitamins" (they often contain 150-200 mcg per serving), are enough to trigger significant changes in thyroid hormone metabolism is surprising. But the evidence is compelling: Decreases of serum T3 and compensatory increases in thyrotropin suggest nothing else but a subclinical hypothyroid response that was triggered by the high(er) selenium intake from day 22-99."
"Composition of the low selenium and high selenium diets fed to men - I would like to point out that there was more than enough iodine in the diets, so this was not the reason the thyroid levels plummeted and the fat began to creep up in the high selenium group."
"In the human study at hand, however, only T3 responded to selenium and in the opposite direction, increasing when selenium was restricted and decreasing when selenium was increased."
"It did thus take no more than 6 weeks on the high vs. low selenium diet to trigger measurable effects not just on the subjects' metabolism, but also on their body weight; and by day 92, the weight gain / loss in the high vs. low selenium groups was pronounced and uniform enough to be statistically significant."
Very worried, as I take supplement (200mcg) and sometimes Brazil nuts on top of that...even more proof that rats are not humans.
Full article:
http://suppversity.blogspot.de/2015/06/too-much-of-good-thing-selenium-little.html
"That "only" 279 mcg/day which is still 30% less than the upper intake level of 400 mcg/day and far away from the toxic range, but only slightly more than what you'll find in many "high potency multi-vitamins" (they often contain 150-200 mcg per serving), are enough to trigger significant changes in thyroid hormone metabolism is surprising. But the evidence is compelling: Decreases of serum T3 and compensatory increases in thyrotropin suggest nothing else but a subclinical hypothyroid response that was triggered by the high(er) selenium intake from day 22-99."
"Composition of the low selenium and high selenium diets fed to men - I would like to point out that there was more than enough iodine in the diets, so this was not the reason the thyroid levels plummeted and the fat began to creep up in the high selenium group."
"In the human study at hand, however, only T3 responded to selenium and in the opposite direction, increasing when selenium was restricted and decreasing when selenium was increased."
"It did thus take no more than 6 weeks on the high vs. low selenium diet to trigger measurable effects not just on the subjects' metabolism, but also on their body weight; and by day 92, the weight gain / loss in the high vs. low selenium groups was pronounced and uniform enough to be statistically significant."
Very worried, as I take supplement (200mcg) and sometimes Brazil nuts on top of that...even more proof that rats are not humans.
Full article:
http://suppversity.blogspot.de/2015/06/too-much-of-good-thing-selenium-little.html
Biffy- Posts : 325
Join date : 2013-03-26
Re: Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
They forgot about iodine (this needs to be in balance), Too much of one or the other creates problems.
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Re: Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
CausticSymmetry wrote:They forgot about iodine (this needs to be in balance), Too much of one or the other creates problems.
Switched over to Lugol's recently. Was doing maybe 6-10 + drops of iosol. What do you recommend for lugols?
NYJets- Posts : 486
Join date : 2012-05-17
Re: Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
The subjects supposedly had enough of Iodine in their diet, though I doubt they supplemented with +12mg of Iodine. I am taking High Selenium Yeast, but the author of the article presented a study (http://www.ncbi.nlm.nih.gov/pubmed/18565425) were there were no observed benefits with 300mcg of High Selenium Yeast, maybe I should switch to L-selenomethionine or just try to get Selenium from diet?
He wrote an alarming article about Iodine also and I know TSH levels return to normal after a while, but still he writes about some really concerning things like: "the evidence that there are real benefits of consuming iodine in the milligram-to-gram range on a daily basis is quasi non-existent, anyways and evidence of a linear or predictable positive relationship between the amount of iodine you consume and your metabolic rate is as non-existent as proven beneficial effects on the gut microbiome, iodine's ability to "flush out toxins" or the "potent anti-oxidant effects" you can read about on the Internet (in fact, high doses are pro-oxidant and may even have necrotic effects, meaning that the will kill cells - good or bad | Many. 1992; Denef. 1996)."
Full article:
http://suppversity.blogspot.de/2015/07/too-much-of-good-thing-iodine-1-mgday.html
He wrote an alarming article about Iodine also and I know TSH levels return to normal after a while, but still he writes about some really concerning things like: "the evidence that there are real benefits of consuming iodine in the milligram-to-gram range on a daily basis is quasi non-existent, anyways and evidence of a linear or predictable positive relationship between the amount of iodine you consume and your metabolic rate is as non-existent as proven beneficial effects on the gut microbiome, iodine's ability to "flush out toxins" or the "potent anti-oxidant effects" you can read about on the Internet (in fact, high doses are pro-oxidant and may even have necrotic effects, meaning that the will kill cells - good or bad | Many. 1992; Denef. 1996)."
Full article:
http://suppversity.blogspot.de/2015/07/too-much-of-good-thing-iodine-1-mgday.html
Biffy- Posts : 325
Join date : 2013-03-26
Re: Higher than RDA intake of Selenium may trigger subclinical hypothyroid response
Those that do purely academic research will undoubtedly be confounded with contradictions.
They are missing out on one of the most health transformation minerals - especially in the wake of the Fukushima era.
In my observation and more importantly the observations of those in the iodine project which is an estimated 40,000 patients strong, have noted a vast number of benefits (one's not commonly known). There's a reason this mineral used to be considered the "cure for everything." Not exactly of course, yet is often used to deal with idiopathic problems.
It is controversial for a simple fact that most clinicians do not go too deep into the both sides of the argument. And yes there are some who simply cannot tolerate the iodine, even in small dosages -- with exception to a organic-whole-food based variety (I have tested this on the most reactive (iodine sensitive types) with no problems. That one is: http://hairevo.com/shop/thyroid-boost/49-thyroid-boost-1-bottle.html
That being said, high dose iodine offers benefits not considered by mainstream.
Here's a long list:
http://www.scribd.com/doc/1959949/IODINE-Solution-to-Healthproblems#scribd
For those who are not iodine sensitive I try them out on a small dose of this...and work it up (some detox will occur the first week).
http://www.iherb.com/TPCS-Iosol-Formula-II-1-fl-oz-30-ml/4785
Lugol's Solution (there's no perfect dosing).....and there are limitations (organification challenges) If this type is used, start small and work the doses higher.
They are missing out on one of the most health transformation minerals - especially in the wake of the Fukushima era.
In my observation and more importantly the observations of those in the iodine project which is an estimated 40,000 patients strong, have noted a vast number of benefits (one's not commonly known). There's a reason this mineral used to be considered the "cure for everything." Not exactly of course, yet is often used to deal with idiopathic problems.
It is controversial for a simple fact that most clinicians do not go too deep into the both sides of the argument. And yes there are some who simply cannot tolerate the iodine, even in small dosages -- with exception to a organic-whole-food based variety (I have tested this on the most reactive (iodine sensitive types) with no problems. That one is: http://hairevo.com/shop/thyroid-boost/49-thyroid-boost-1-bottle.html
That being said, high dose iodine offers benefits not considered by mainstream.
Here's a long list:
http://www.scribd.com/doc/1959949/IODINE-Solution-to-Healthproblems#scribd
For those who are not iodine sensitive I try them out on a small dose of this...and work it up (some detox will occur the first week).
http://www.iherb.com/TPCS-Iosol-Formula-II-1-fl-oz-30-ml/4785
Lugol's Solution (there's no perfect dosing).....and there are limitations (organification challenges) If this type is used, start small and work the doses higher.
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
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