Quercetin as crth2 blocker

angusmojo Wed May 09, 2012 8:53 am

Hi Caustic,

I used to have very good results w/ quercetin but had to reduce a lot my intake from 1g/day (in 2 takes) to 200mg, due to very bad heart feeling. Have you experienced that? I objectively can reproduce it all the time I take more than this amount...

So I'd like to give a try to a topical usage of quercetin but am concerned about the yellow color that apparently sticks to the skin several days.
Do you have a workaround to mitigate this? Or an analog to quercetin to recommend?

It's a pity because quercetin reduces totally inflammation and under a big amount intake had drasticaly improve my hair.

Some guys on HLT for instance start trying crth2 antagonist like oc000459, are you aware of other natural players against this pathway than quercetin?

TIA

nidhogge Wed May 09, 2012 11:11 am

Angus,

There is a good chance that CS and I will add a good quality Quercetin extract to Antioxidant Boost in the near future, at 100 mg per pill. Since the dosage is two pills a day, it would equate to 200mg. This would help to enhance the effect of the trans-resveratrol and curcumin.

imprisoned-radical Wed May 09, 2012 12:49 pm

angusmojo wrote:Hi Caustic,

I used to have very good results w/ quercetin but had to reduce a lot my intake from 1g/day (in 2 takes) to 200mg, due to very bad heart feeling. Have you experienced that? I objectively can reproduce it all the time I take more than this amount...

So I'd like to give a try to a topical usage of quercetin but am concerned about the yellow color that apparently sticks to the skin several days.
Do you have a workaround to mitigate this? Or an analog to quercetin to recommend?

It's a pity because quercetin reduces totally inflammation and under a big amount intake had drasticaly improve my hair.

Some guys on HLT for instance start trying crth2 antagonist like oc000459, are you aware of other natural players against this pathway than quercetin?

TIA

Just eat a baked red onion. I wonder if quercetin alone at 1g/day could cause heart-related symptoms, because I've read about studies in which subjects tolerated much larger doses. This leads me to think that there's some other ingredient in the supplement that might be causing you problems, but I could be wrong. Why would you want to continue with a supplement that causes you to experience heart-related symptoms? Even if you've reduced the dosage significantly, why would anybody want to take that risk? How do you know it's not doing damage that you can't actually feel?

Just recently read a study showing that supplementation with concentrated green tea extracts can cause liver damage. I know this forum is big on supplementation, but you should be aware that no matter how "natural" a substance is, our bodies are not necessarily prepared to take it as a supplement containing an amount many hundred times greater than what would occur naturally in food. Especially when it's processed and other cofactors are removed.

angusmojo Wed May 09, 2012 5:19 pm

imprisoned-radical wrote:
angusmojo wrote:Hi Caustic,

I used to have very good results w/ quercetin but had to reduce a lot my intake from 1g/day (in 2 takes) to 200mg, due to very bad heart feeling. Have you experienced that? I objectively can reproduce it all the time I take more than this amount...

So I'd like to give a try to a topical usage of quercetin but am concerned about the yellow color that apparently sticks to the skin several days.
Do you have a workaround to mitigate this? Or an analog to quercetin to recommend?

It's a pity because quercetin reduces totally inflammation and under a big amount intake had drasticaly improve my hair.

Some guys on HLT for instance start trying crth2 antagonist like oc000459, are you aware of other natural players against this pathway than quercetin?

TIA

So true.

I plan to test another version. Now on Natrol w/ indeed other ingredient than pure quercetin...

Nobody on quercetin topicaly?

Just eat a baked red onion. I wonder if quercetin alone at 1g/day could cause heart-related symptoms, because I've read about studies in which subjects tolerated much larger doses. This leads me to think that there's some other ingredient in the supplement that might be causing you problems, but I could be wrong. Why would you want to continue with a supplement that causes you to experience heart-related symptoms? Even if you've reduced the dosage significantly, why would anybody want to take that risk? How do you know it's not doing damage that you can't actually feel?

Just recently read a study showing that supplementation with concentrated green tea extracts can cause liver damage. I know this forum is big on supplementation, but you should be aware that no matter how "natural" a substance is, our bodies are not necessarily prepared to take it as a supplement containing an amount many hundred times greater than what would occur naturally in food. Especially when it's processed and other cofactors are removed.

nidhogge Sat May 12, 2012 4:16 am

Because of how yellow it is, I've ruled out Quercetin topically a few years back. Perhaps it's OK if you want to leave it in as an over-night topical, but stuff like that you tend to stick with for a month or two then the hassle causes you to gradually cease application.

nidhogge Sat May 19, 2012 2:27 am

imprisoned-radical wrote:
angusmojo wrote:Hi Caustic,

I used to have very good results w/ quercetin but had to reduce a lot my intake from 1g/day (in 2 takes) to 200mg, due to very bad heart feeling. Have you experienced that? I objectively can reproduce it all the time I take more than this amount...

So I'd like to give a try to a topical usage of quercetin but am concerned about the yellow color that apparently sticks to the skin several days.
Do you have a workaround to mitigate this? Or an analog to quercetin to recommend?

It's a pity because quercetin reduces totally inflammation and under a big amount intake had drasticaly improve my hair.

Some guys on HLT for instance start trying crth2 antagonist like oc000459, are you aware of other natural players against this pathway than quercetin?

TIA

Just eat a baked red onion. I wonder if quercetin alone at 1g/day could cause heart-related symptoms, because I've read about studies in which subjects tolerated much larger doses. This leads me to think that there's some other ingredient in the supplement that might be causing you problems, but I could be wrong. Why would you want to continue with a supplement that causes you to experience heart-related symptoms? Even if you've reduced the dosage significantly, why would anybody want to take that risk? How do you know it's not doing damage that you can't actually feel?

Just recently read a study showing that supplementation with concentrated green tea extracts can cause liver damage. I know this forum is big on supplementation, but you should be aware that no matter how "natural" a substance is, our bodies are not necessarily prepared to take it as a supplement containing an amount many hundred times greater than what would occur naturally in food. Especially when it's processed and other cofactors are removed.

imprisoned-radical--

While it's true that super-dosing on some herbs can cause side-effects, it doesn't appear that is the case with Quercetin in my studies. In fact, Quercetin is listed as having no side-effects regardless of dosage size, and is commonly recommended at a few grams a day.

j87x Sat May 19, 2012 6:00 am

Found some white quercetin, not sure how pure or good it is though.
http://www.alibaba.com/product-gs/219561594/Quercetin.html
http://www.alibaba.com/product-gs/537049981/Quercetin_98_.html

angusmojo Fri May 25, 2012 8:08 am

Indeed, I switched to pure quercetin and I don't get the same issue than w/ the natrol combo.

Right now, I'm on 100mg of quercetin in the morning and i get almost no inflammation until the evening. Topicaly, i apply astressin b (from the topical that contains a few ppm) in the morning and in the evening.
Really, quercetin improves against inflammation. Last week, following the cetirizin trend (pgd2) i diluted one 10mg pill of zyrtec (cetirizine) in my topical bottle and frankly it may be subjective but I feel that it helps. Following the pge1 trend (good for hair growth, contrary to pgd2 and derivative 15-dPGD2 which appear to be responsible of hair shrink), I'm starting a diet rich in GLA (increase PGE1).

CausticSymmetry Fri May 25, 2012 8:43 am

I've been using this form, because of the phospholipid factor (keeps it in circulation for longer:

http://www.iherb.com/MRM-Quercetin-500-mg-60-Veggie-Caps/12059?at=hil335

Bye Wed May 30, 2012 11:15 pm

Has somebody once Korres Quercetin and Oak Creame tested against hair loss?
This could be an alternative maybe.
Bye

angusmojo Thu May 31, 2012 12:54 am

Bye wrote:Has somebody once Korres Quercetin and Oak Creame tested against hair loss?
This could be an alternative maybe.
Bye

I bought Korres Quercetin & Oak antiwrinkle night cream and applied it during one week and had immediate shedding. As there are so many things in cosmetic creams, it's difficult to attribute it to quercetin topicaly applied.
Ideally, if online diy cosmetic shop would provide quercetin as ingredient, we could know if it's efficient, but no one provides quercetin or luteolin...

Sponsored content

Quercetin as crth2 blocker

Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker

Korres Quercetin and Oak

Re: Quercetin as crth2 blocker

Re: Quercetin as crth2 blocker