Absorbable nutrients: Factors

It's come to my understanding that nutrients are absorbed differently and that the uptake varies depending on which form the nutrient is in, or simply put, what kind of carrier molecule it has a bound to. I would like to understand more about this process and why, for example, minerals in "free form" doesn't get absorbed but when attached to, let's say, picolinate, or the less (?) potent one, sulfate, the body can assimilate it.

I would like to know all these factors.

Bump!

Compounds that are more fat-soluble should be consumed along with a fatty meal. This includes vitamins A, D, E, K, and plant phenols like curcumin and resveratrol. The fat in the meal stimulates the release of bile from the liver and gall bladder, and the bile is required to break down the fat in the small intestines.

Something else to consider is enzymatic metabolism in the liver and intestinal epithelium. Compounds can under go methylation, sulfation, and glucuronidation prior to entering circulation and the metabolites might not have the same pharmacological properties.