Pregnenolone

I just starting using the cream. How long should I try this out and should I be supplementing with anything else while on it? Ive read its good to supplement with T3 and T4.

bh1546 wrote:I just starting using the cream. How long should I try this out and should I be supplementing with anything else while on it? Ive read its good to supplement with T3 and T4.

Why are you supplementing preg?

I believe I may have adrenal fatigue...ever since I got off fin I have had chronic inflammation on my scalp and feel like it has messed with my hormones a bit. I also had to take prednisone a couple weeks ago and I had zero inflammation while taking it.

For adrenal fatigue try the miracle adrenal mix - 1/4 tsp potassium chloride, 1/4 tsp of sea salt, 1/2 tsp ascorbic acid mixed in a liter of water.

For how many days?

Hi bh1546,

Any update using the pregnenolone cream for adrenal fatigue?

Hey, I quite using it after 4 days...I felt it made me feel real anxious and jittery. Not sure what this means.

bh1546 wrote:Hey, I quite using it after 4 days...I felt it made me feel real anxious and jittery. Not sure what this means.

This happens to some people when using the transdermal delivery. When this occurs, it is suggested to go the oral route. Generally, though the transdermal method is preferred.

On a more practically level, optimizing vitamin D levels is one of the most natural and effective ways to increase your neurosteroid levels. This takes between 4 and 6 months usually.

Thanks for the info CS. What brand of Vit D supp do you recommend and how much per day?

@bh1546 here's an article CS wrote on vitamin D, it might help

http://healthyfixx.com/40/how-much-vitamin-d-should-you-take

Hi guys,

I have now tried transdermal pregnenolone for a little week and I have been experiencing something similar as "bh1546" with anxiety and jittery etc. I took it in the morning (15 mg) and actually felt good until noon where the anxiety started.

Could it be the dosage (15 mg)? Will try a smaller amount or go the oral route´.

I have also tried the locorice, b5 and raw thyroid route, and it gave me a similar feeling. Does this perhaps mean that I don't have adrenal fatique?

My situation is that I am pretty sure I am hypothyroid (TSH = 4.2 and have been using SSRI's in the past for a short while). Therefore I take Iodine + co-factors which really help my hair loss and inflammation, but lately it have made me very tired, so I suspect that I also have adrenal fatigue (not just from the iodine - I have had trouble gaining weight, feeling depressed, irritated and being tired before).

Something that seems to help better is a combination af iodine (+ co-factors) and the raw thyroid supplement. This dosen't make me feel anxious and gives med more energy, so will try this for a while!

I used the oral pregnenolone before trying the topical and didn't see any benefits. A week after trying the topical is when I was amazed how effective it was for stress and related issues.

The raw thyroid might also have raw adrenal in it and that might be helping you.

Hey guys,

I now tried the oral pregnenolone (sublingual 10 mg) and although it really helped with fatigue like the transdermal, after 3 hours or so it makes me really irritated, same thing as with the transdermal. Anyone know why that might be?

Actually the same thing happens with the adrenal building method, when using B5, raw thyroid and licorice. So it seems that whenever I take something that can raise cortisol I don't feel tired enymore but instead I become very irritable even at low doses.

I feel tired all the time, but can't figure out why as I eat well and go to bed on normal times etc.

Any thoughts on this? every sugestion is really appriciated!!

I also get more energy hours after using the topical. But that's to be expected since it affect the adrenal which is an energy center.

However, I haven't noticed getting more irritable after. It could be from other health factors such as hormones or thyroid. I know that salt loading even when not using Iodine, works on my adrenals with the effect of lessening irritation and stress. So that might help with your situation.

Thanks for the reply zero,

I have actually been salt loading for some time, because I have been taking iodine. It helps some, but I still feel tired even without taking iodine. I do suspect a thyroid issue since I have a lot of the symptoms and I have tried Iodine + co-factors for time now, even days with 150 mg... but still my tiredness exists, though iodine has been the one thing that can stop my hair loss. Im also sure its not the detox reaction from iodine, since its been going on for a very long time, even before iodine.

Basically I'm feeling great on pregnenolone, if I wouldn't get so irritated by using it. Any ideas as to why that is?

*disregard this

You seem to have a lot of things covered the Vikingo. I just now did a search on pregnenolone and irritability and came across DHEA causing irritability as well. One thing that might help is to reduce the amount you use and see if the irritability subsides while still getting positives. Or maybe stop using it and see if you even need it at all. Maybe you have enough hormones already and this is adding to that and overloading you with DHEA and other hormones. You could even be overdosing on adrenal tonics or just supplements that affect them.

I would try low dose pregnenolone (5-10mg) at first. Give your body a while to find hormonal homeostasis. Otherwise, pregnenolone not only made me slightly edgy, it gave me restless leg syndrome before balancing out after a few months.

Thats why I stopped after a few days...I was feeling very anxious. 40 you feel better than before you started taking it after everything balanced out?

Hey bh1546,

I have been reading a bit on the http://www.musclechatroom.com forum and found a lot of interesting things about pregnenolone.

I am now trying to take it at night time (15mg TD, might need to get a little lower) and that has been a lot better than taking i during the day. I felt better when i woke up, with almost no irritability etc.

On the musclechatroom fourm, some of the ideas from "Chillin" are:

1. If it gives you anxiety etc then lower the dose of preg and use it together with progesterone.

2. If your body needs more cortisol that the ACTH can handle (maybe because of murcury toxisity or thyroid issues) then you need to take replacement doses for a while. These doses are in the range of 500mg transdermal pregnenolone... the oral won't work here.

I suggest you take at look at the musclechatroom as I couldn't remember everything... there is also a very good dosage guide etc.

Viking, thanks for the info I will look into it. Also, If I remember correctly I remember IH saying that vitamin D supplementation also helps correct or balance everything out but it can take a while. Any experience with this?

No problem. I am kind of in the same boat as you.

I have used vitamin D several times, at first looking like it really helped balance hormones and made me more relaxed and outgoing, but then after a while I believe it caused some hair loss and inflammation, so I dropped it. I used the one IH has on his top six.

Report back if you experience anything interesting with pregnenolone!