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Anti-Histamines and Scalp Itch

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Anti-Histamines and Scalp Itch Empty Anti-Histamines and Scalp Itch

Post  helpmyhair1 Wed Aug 03, 2011 5:39 am

I've always had allergies for as long as I can remember... and have been taking anti-histamines (Reactine) for a long time. I notice on some nights when I have some pretty rough scalp itch and slight itching elsewhere on my body, that taking a reactine helps the scalp itch as well, and decreases it pretty signicantly. Could my scalp itch be caused by allergies? or at least heightened by it? Is using Reactine bad for hair?

thanks

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Anti-Histamines and Scalp Itch Empty Re: Anti-Histamines and Scalp Itch

Post  mphatesmpb Wed Aug 03, 2011 5:57 am

Mast cell degranulation has been observed in MPB hair follicles. It's the process by which resident white blood cells release chemical signals into the surrounding interstitium, initiating an inflammatory process. This faulty immune response is an often overlooked component of MPB.

Maybe the anti-histamine agent you're taking prevents mast cell degranulation.
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Post  magic_gro Wed Aug 03, 2011 7:38 am

somewhere else on this forum people pointed to a study on endocannabinoids affecting the hair: https://immortalhair.forumotion.com/t4770-cannabinoids-inhibit-hair-growth

but, if mast cell degranulation has a role in MPB, then the endocannabinoid PEA (palmitoylethanolamide) should help downregulate mast cell degranulation better than anything else.

i had just started trying it towards the end of 2010 - both systemically via a tablet and topically on my temples via a cream - when i read the above post, got scared and decided to stop it.

CS and others, what's your take?

thanks!
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Post  CausticSymmetry Thu Oct 08, 2015 6:07 pm

I wrote an article about this quite some time ago. This is a plus for hair. Not to be confused with other studies which are unrelated.

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