Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota

For #curcumin (#CUR) and #resveratrol (#RSV) 1 + 1 equal 0.5, not 2! - Bad news for the "I just take everything supplement junkies":

"Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota"

#Rodent Study designed estimate the respective effect of RSV and Cur alone or in association on the control of glycemia and on gut microbiota finds that a 5-week chronic treatment of hyperglycemic mice with RSV and/or Cur resulted in a differential effect on glucose tolerance test and modified gut microbiome.

"We precisely identified groups of bacteria representing a specific signature of the glycemic effect of RSV," the authors point out and explain that it's a potential interference effect of the two that explains why #cur alone, but not #cur+#rsv had beneficial effects on glucose management in their study.

suppversity.com | https://www.sciencedirect.com/science/article/abs/pii/S0955286319301548?fbclid=IwAR1EQO0rW6DJy8QU0VBN1Obrg8l8lwUtML5JBZa9MHmstR_wb9gCQevSNpY