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OT: could someone provide an example (with linked studies) of something happening in vitro but not being the case in vivo?

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OT: could someone provide an example (with linked studies) of something happening in vitro but not being the case in vivo? Empty OT: could someone provide an example (with linked studies) of something happening in vitro but not being the case in vivo?

Post  sizzlinghairs Sat Oct 10, 2015 7:01 am

I'm just trying to understand it all better.

Thanks in advance!

sizzlinghairs

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OT: could someone provide an example (with linked studies) of something happening in vitro but not being the case in vivo? Empty Re: OT: could someone provide an example (with linked studies) of something happening in vitro but not being the case in vivo?

Post  Changexpert Sat Oct 10, 2015 10:42 am

As far as I know, one contributing factor is a presence of an inhibitory or stimulating feedback loop. Different processes can occur based on the level of different enzymes, cofactors, and reactants as well.

Example of T metabolism
http://www.ncbi.nlm.nih.gov/pubmed/6950919
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