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Wes Welker Hair Transplant
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TrueGround
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CausticSymmetry
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AS54
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Re: Wes Welker Hair Transplant
sanderson - You are referring to the "NO-ONO" cycle.
Ecklonia cava helps deal with peroxynitrate. Also in some user people, the enzyme
The enzyme ornithine decarboxylase (ODC) can be problematic if it's too low (it is necessary for
ammonia dumping) and also is important for hair growth.
Ecklonia cava helps deal with peroxynitrate. Also in some user people, the enzyme
The enzyme ornithine decarboxylase (ODC) can be problematic if it's too low (it is necessary for
ammonia dumping) and also is important for hair growth.
_________________
My regimen
http://www.immortalhair.org/mpb-regimen
Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
Re: Wes Welker Hair Transplant
Slowmoe,
No need sir. Just found these. Incredibly interesting.
http://cancerres.aacrjournals.org/content/72/4_Supplement/B8.abstract
http://www.ncbi.nlm.nih.gov/pubmed/21856910
It would appear as if the androgens, specifically DHT, attenuate the hypoxic condition. This is a very convincing pathway for local increase in DHT:Estradiol ratios.
It would also add weight to the cellular views of hypoxic stress, given that mitochondrial dysfunction or ROS-related stress is the cellular version of hypoxia.
This actually provides us two different factors for examining the cause of hypoxia: 1) blood flow/respiratory function and 2) mitochondrial function
1) obviously oxygen delivery relies on blood flow
2) without metabolism of that oxygen, it just an angry ROS floating around causing damage; the mitochondria must be functioning and have carbohydrate fuel in sufficient amounts to actually use the oxygen, otherwise despite having a sufficient amount of oxygen intercellularly, you are not using it to produce energy
For that reason, I think a manual-only approach might be ignoring half of the puzzle. Unless the machinery is using oxygen, it might as well not even be there to begin with.
http://www.ncbi.nlm.nih.gov/pubmed/16815102
http://www.ncbi.nlm.nih.gov/pubmed/15896810
Mitochondrial dysfunction is considered genetic hypoxia. It has been shown to disrupt so many different pathways, and also disrupts protein unfolding, and induces heat shock proteins, which CS posted a study recently showing these to be elevated in hair loss. Ultimately, dysfunction at the level of the mitochondria could precipitate the decline in vascular health that leads to lowered blood flow, a vicious cycle.
For me this is absolutely key, and helps us tie up so many connections to hair loss that we have had trouble relating before, specifically it helps to explain the connection between blood sugar problems, high insulin, and hair loss. (diabetes and insulin resistance are essentially mitochondrial diseases, even pathogen induced insulin resistance is more than likely due to oxidative stress at the cellular level).
No need sir. Just found these. Incredibly interesting.
http://cancerres.aacrjournals.org/content/72/4_Supplement/B8.abstract
http://www.ncbi.nlm.nih.gov/pubmed/21856910
It would appear as if the androgens, specifically DHT, attenuate the hypoxic condition. This is a very convincing pathway for local increase in DHT:Estradiol ratios.
It would also add weight to the cellular views of hypoxic stress, given that mitochondrial dysfunction or ROS-related stress is the cellular version of hypoxia.
This actually provides us two different factors for examining the cause of hypoxia: 1) blood flow/respiratory function and 2) mitochondrial function
1) obviously oxygen delivery relies on blood flow
2) without metabolism of that oxygen, it just an angry ROS floating around causing damage; the mitochondria must be functioning and have carbohydrate fuel in sufficient amounts to actually use the oxygen, otherwise despite having a sufficient amount of oxygen intercellularly, you are not using it to produce energy
For that reason, I think a manual-only approach might be ignoring half of the puzzle. Unless the machinery is using oxygen, it might as well not even be there to begin with.
http://www.ncbi.nlm.nih.gov/pubmed/16815102
http://www.ncbi.nlm.nih.gov/pubmed/15896810
Mitochondrial dysfunction is considered genetic hypoxia. It has been shown to disrupt so many different pathways, and also disrupts protein unfolding, and induces heat shock proteins, which CS posted a study recently showing these to be elevated in hair loss. Ultimately, dysfunction at the level of the mitochondria could precipitate the decline in vascular health that leads to lowered blood flow, a vicious cycle.
For me this is absolutely key, and helps us tie up so many connections to hair loss that we have had trouble relating before, specifically it helps to explain the connection between blood sugar problems, high insulin, and hair loss. (diabetes and insulin resistance are essentially mitochondrial diseases, even pathogen induced insulin resistance is more than likely due to oxidative stress at the cellular level).
Last edited by anthonyspencer54 on Fri Jun 28, 2013 5:10 am; edited 2 times in total
AS54- Posts : 2367
Join date : 2011-08-12
Age : 35
Location : MI
Re: Wes Welker Hair Transplant
http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2011;volume=2;issue=1;spage=178;epage=178;aulast=Kemp
Comprising five layers, the scalp is bound by the face anteriorly and the neck laterally and posteriorly.
---The skin is the first layer.
---The second layer is connective tissue, which is a thin layer of fat and fibrous tissue with a thickness of 4-7 mm.
---The third layer is the galea aponeurotica, which exists as a tough layer of dense fibrous tissue that extends between the frontalis and occipitalis muscles.
---Deep to these layers, the loose areolar connective tissue comprises collagen bundles and houses the major blood vessels of the scalp. This layer is laterally attached to the zygomatic arch and mastoid processes and posteriorly attached to the superior nuchal line. This layer provides the separation plane for surgical flaps and traumatic avulsions. [11] The final layer is the pericranium, which is the periosteum of the skull. This layer ends laterally with the origin of the temporalis fascia along the superior temporal line and provides nutrient supply to the bone
So if a person had varying degrees of muscle tension and weak loose connective tissue bloodflow could be significantly disturbed in the galea region....
Comprising five layers, the scalp is bound by the face anteriorly and the neck laterally and posteriorly.
---The skin is the first layer.
---The second layer is connective tissue, which is a thin layer of fat and fibrous tissue with a thickness of 4-7 mm.
---The third layer is the galea aponeurotica, which exists as a tough layer of dense fibrous tissue that extends between the frontalis and occipitalis muscles.
---Deep to these layers, the loose areolar connective tissue comprises collagen bundles and houses the major blood vessels of the scalp. This layer is laterally attached to the zygomatic arch and mastoid processes and posteriorly attached to the superior nuchal line. This layer provides the separation plane for surgical flaps and traumatic avulsions. [11] The final layer is the pericranium, which is the periosteum of the skull. This layer ends laterally with the origin of the temporalis fascia along the superior temporal line and provides nutrient supply to the bone
So if a person had varying degrees of muscle tension and weak loose connective tissue bloodflow could be significantly disturbed in the galea region....
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: Wes Welker Hair Transplant
The results of treatment in the clinical trial:
Excellent 15%
Lanugo (vellus hair) developed
back to strong terminal hair. Average thick
Hair grew back thicker than before. Compacted hair growth
themselves. complete on the head area
Good 25%
The effects described above occurred primarily at
on the edges of hair loss.
Partial improvement of 25%
The improvements described above occurred, but
with little regrowth.
No change 35%
There were no changes detected.
For the clinical study of 40 subjects, the system was used for a year daily for 2 hours
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: Wes Welker Hair Transplant
Slowmoe,
If androgen receptor activity and DHT production are up-regulated in hypoxic conditions, why on earth would you want one of those things choking off blood flow to your scalp for 2 hrs?
If androgen receptor activity and DHT production are up-regulated in hypoxic conditions, why on earth would you want one of those things choking off blood flow to your scalp for 2 hrs?
TrueGround- Posts : 208
Join date : 2012-01-05
Re: Wes Welker Hair Transplant
TrueGround wrote:
Slowmoe,
If androgen receptor activity and DHT production are up-regulated in hypoxic conditions, why on earth would you want one of those things choking off blood flow to your scalp for 2 hrs?
It doesn't choke it off; it pulls the scalp muscles loose (stretches them) and makes the galea loose by pushing the skin toward the top center of your skull. The blood vessels where the device sits have a padding of hair, fat and muscle to keep them from getting restricted. When I wear mine, my inflammation goes down greatly and the following day my scalp seems to stay much looser.. Noticing big improvements in my vertex since using this, emu oil and violet ray
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: Wes Welker Hair Transplant
Hmmm..
Got a link to purchase that device?
Got a link to purchase that device?
TrueGround- Posts : 208
Join date : 2012-01-05
Re: Wes Welker Hair Transplant
TrueGround wrote:Hmmm..
Got a link to purchase that device?
http://www.ac-therapie.de/AC-Tension-Reliever.161.0.html
Use google translate...It is 500 euro I believe
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: Wes Welker Hair Transplant
SlowMoe wrote:TrueGround wrote:
Slowmoe,
If androgen receptor activity and DHT production are up-regulated in hypoxic conditions, why on earth would you want one of those things choking off blood flow to your scalp for 2 hrs?
It doesn't choke it off; it pulls the scalp muscles loose (stretches them) and makes the galea loose by pushing the skin toward the top center of your skull. The blood vessels where the device sits have a padding of hair, fat and muscle to keep them from getting restricted. When I wear mine, my inflammation goes down greatly and the following day my scalp seems to stay much looser.. Noticing big improvements in my vertex since using this, emu oil and violet ray
did you purchase the one you linked to or is this the one you created yourself?
@CS, thanks for the tip on that enzyme reaction. i actually have l-orthinine and purchased it for ammonia detoxification so it makes sense from the name. i didn't know why it helps. i'll do some more research into that to see if i have a possible issue with it.
sanderson- Posts : 1198
Join date : 2012-03-13
Re: Wes Welker Hair Transplant
sanderson wrote:SlowMoe wrote:TrueGround wrote:
Slowmoe,
If androgen receptor activity and DHT production are up-regulated in hypoxic conditions, why on earth would you want one of those things choking off blood flow to your scalp for 2 hrs?
It doesn't choke it off; it pulls the scalp muscles loose (stretches them) and makes the galea loose by pushing the skin toward the top center of your skull. The blood vessels where the device sits have a padding of hair, fat and muscle to keep them from getting restricted. When I wear mine, my inflammation goes down greatly and the following day my scalp seems to stay much looser.. Noticing big improvements in my vertex since using this, emu oil and violet ray
did you purchase the one you linked to or is this the one you created yourself?
I made my own
SlowMoe- Posts : 1112
Join date : 2012-03-22
Re: Wes Welker Hair Transplant
SlowMoe wrote:http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2011;volume=2;issue=1;spage=178;epage=178;aulast=Kemp
Comprising five layers, the scalp is bound by the face anteriorly and the neck laterally and posteriorly.
---The skin is the first layer.
---The second layer is connective tissue, which is a thin layer of fat and fibrous tissue with a thickness of 4-7 mm.
---The third layer is the galea aponeurotica, which exists as a tough layer of dense fibrous tissue that extends between the frontalis and occipitalis muscles.
---Deep to these layers, the loose areolar connective tissue comprises collagen bundles and houses the major blood vessels of the scalp. This layer is laterally attached to the zygomatic arch and mastoid processes and posteriorly attached to the superior nuchal line. This layer provides the separation plane for surgical flaps and traumatic avulsions. [11] The final layer is the pericranium, which is the periosteum of the skull. This layer ends laterally with the origin of the temporalis fascia along the superior temporal line and provides nutrient supply to the bone
So if a person had varying degrees of muscle tension and weak loose connective tissue bloodflow could be significantly disturbed in the galea region....
That's mostly Latin to me. I just want to interject that there's no evidence that people with connective tissue disorders are more prone to hair loss than normal individuals. Not that I'm closed to the idea of low-level hypoxia being involved in alopecia.
takingaction- Posts : 228
Join date : 2008-12-25
Re: Wes Welker Hair Transplant
Optimal fitness doesn't always equal optimal health.
MilBA- Posts : 142
Join date : 2009-11-12
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Similar topics
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