Olive Oil Phenols Inhibit Human Hepatic Microsomal Activity

>>>> Olive leaf extract is a better source than olive oil .. It boosts 17b-hsd oxidative (type 2, 4, 8 ) that converts from strong estradiol to weak estrone, by gallic acid. Oleuropein inhibits 17b-hsd reductive. This could be highly beneficial.

Olive Oil Phenols Inhibit Human Hepatic Microsomal Activity
Ieva Stupans1, Graham Stretch and Peter Hayball

Center for Pharmaceutical Research, School of Pharmacy and Medical Sciences, University of South Australia, SA, 5000, Australia

We have examined the inhibition of human hepatic microsomal androstenedione 6ß-hydroxylation and both reductive and oxidative 17ß-hydroxysteroid dehydrogenase (17ß-HSD) activity by complex phenols found in olive oil. Structurally similar compounds were also examined for comparison. Androstenedione 6ß-hydroxylase activity was inhibited by oleuropein glycoside, hydroxytyrosol and gallic acid. Oleuropein glycoside, hydroxytyrosol, gallic acid and dihydroxybenzoic acid also inhibited reductive 17ß-HSD activity. Oxidative 17ß-HSD activity was not inhibited by any of the compounds tested; however gallic acid stimulated activity by ~30%


http://jn.nutrition.org/cgi/content/full/130/9/2367

What does this mean?

Scotty, I think it means Olve leaf extract rich in Oleuropein might be good for hair since it modulates etrogen metabolism of 17ß-HSD reductive in both men and females.

I also read another study, when taken on full stomach it has a half-life of 12 hours.

It also is a strong antioxidant. It aids in prober digestion. It kills bacteria and virus, and lowers blood pressure from 138 to 126 according to study.