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Vitamin A / D3 Balance to restore mucosal immunity, resolve gut issues -- Updated

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Post  LittleFighter Thu Jul 05, 2012 1:51 pm

For the last few months, I've been taking this combo in sufficient amounts with fantastic results. I have more resistance to bad food (wheat, commercial milk) and don't get the symptoms that plagued me before. My gut is working just fine. Skin is great and dandruff vanished. For some reason, it doesn't surprise me, but this is very significant. In the case of dandruff, I have posted information and evidence that it's linked to yeast overgrowth and the gut plays a role in its development. BTW, I have the genotype that is reported to produce much less vitamin A in the body, requiring an increase in dietary intake. Is Vitamin A a missing link for some and a variety of conditions?

Vitamin A and D work in tandem, not in isolation. One protects against toxicity from the other. Vitamin K2 also plays a role in forming Vitamin K dependent proteins. Vitamin A is important for thyroid function. Vitamin A with D3 inhibits inflammation and calms the immune system. Want to rise SIgA levels and reduce leaky gut? Vitamin A (in balance) to the rescue.

I would recommend 10,000 IUs of natural vitamin A (NOT beta-carotene, but Animal-derived Vitamin A like Cod Liver Oil) and 4,000-5000 IUs of D3 (more or less, it depends on each person) per day.

Only doing Vitamin D3 for long periods is doing more harm than good in the long term, according to some.

I will concentrate info on this thread as soon as I have time. Just wanted to get this started.


Updated


  • http://www.westonaprice.org/blogs/cmasterjohn/2012/01/22/new-evidence-of-synergy-between-vitamins-a-and-d-protection-against-autoimmune-diseases/

  • http://suppversity.blogspot.com/2012/05/anti-vitamin-effects-of-beta-carotene.html

  • http://drbganimalpharm.blogspot.mx/2008/03/free-to-wear-sunscreen-vitamin-ds-co.html

    Synergy between Vitamin A and D - You might need to lower your D3 supplementation

    "Both A and D are fat-soluble vitamins, co-factors and synergize each other's respective actions and I believe blood concentrations (like the addition of other steroid nuclear receptor agonists increases Vitamin D blood concentrations, and... vice versa. Yes...The latter has been demonstrated anecdotally. Rare studies also confirm this phenomenon). Therefore, it's prudent to reduce vitamin D supplementation if you begin vitamin A supplementation... and t-r-a-c-k i-t . Smile"

  • http://suppversity.blogspot.com/2011/06/put-a-to-d-ongoing-supplementation-with.html

  • http://www.nleducation.co.uk/resources/reviews/probiotics-make-dendritic-cells-stop-singing-the-blues/

  • http://www.nleducation.co.uk/resources/reviews/vitamin-a-the-key-to-a-tolerant-immune-system/

    "The availability of vitamin A in our food is a key factor in a tolerant, highly functional immune system. To quote from the title of a brilliant commentary in the March 2008 issue of Nature’s Mucosal Immunology, “Vitamin A rewrites the ABCs of oral tolerance.”

    The council considers supplements of 10,000 IU daily of preformed vitamin A (retinol) to be generally safe. They note a long history of safe use of supplements containing up to 10,000 IU daily. Those who regularly consume liver or organ meats may be getting enough from their diet and may exercise more caution about vitamin A supplements.

    Our friend, our helper, is vitamin A, a beautiful nutrient, like vitamin D. Both are sophisticated and capable of wonderful things, but having too much or too little of either one interferes with the other’s capacity to be lovely."




Last edited by LittleFighter on Fri Jul 06, 2012 9:03 am; edited 4 times in total
LittleFighter
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Post  CausticSymmetry Thu Jul 05, 2012 1:54 pm

This is my belief also. For that reason, I've been advising many of my clients to take animal form vitamin A.

More info here:

http://healthyfixx.com/33/why-vitamin-a-is-more-important-than-you-think

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Post  LittleFighter Thu Jul 05, 2012 1:56 pm

Previously I taked a sufficient dose of Vitamin D3 with not much effects. Then I added A LITTLE bit of Vitamin A with no apparent results. Finally I added 10,000 IU daily and after some time I experienced REAL changes, skin, scalp, how I feel, etc.

That's a great article CS!
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Post  gg4545 Thu Jul 05, 2012 3:05 pm

has that been the entire regimen littlefighter?? how do you feel about acidophilus as a probiotic also??

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Post  LittleFighter Thu Jul 05, 2012 3:15 pm

Bacteria IS needed for the proper function of the immune system, tolerance, etc.

Eat the fiber from veggies, herbs, fruits and berries, that feeds gut bacteria.

A safe, proven and tolerable probiotic I always recommend is Lactobacillus GG. This one is antiinflammatory. Other option is S. Boulardii. Other probiotics are much less proven.

There is some evidence that a high meat (and sat fat) and no fiber diet is not good for your gut. There's been discussion (from major ignorance) from Paleo promoters stating that you don't need fiber or veggies... I believe that drives your gut towards an inflammatory state. Add nourishment for your gut flora. We are seeing increasing evidence that your gut flora might be one of the single most important and significant aspect of health.

My regimen: I take krill oil, vit a/d3/k2, garlic, ecklonia cava, food based vitamins, astaxanthin, betaine hcl, a cleansing fiber, and a few other items. I'm gonna try other stuff soon.
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Post  LittleFighter Thu Jul 05, 2012 3:21 pm

I forgot to mention. I will try a mix of some bulk prebiotics to boost gut health.

There are interesting studies showing how they shift gut flora in the right direction, reduce insulin, glucose, etc.
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Post  gg4545 Thu Jul 05, 2012 3:23 pm

do you know what prebiotic you will try or just giving a few different one's a go?

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Post  LittleFighter Thu Jul 05, 2012 3:26 pm

Fibersol-2 and FOS.

http://www.nutraingredients-usa.com/Research/Inulin-plus-resistant-starch-could-be-super-prebiotic

Sounds interesting.


Just keep in mind that when a company that produces a product funds research, the results are predictable. In this case, this seems legit, and you can see the effects right away (better stools, less odor, even less anxiety!).
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Post  gg4545 Thu Jul 05, 2012 3:33 pm

yeah i know lol info looks good though!!

About the lacto gg what kind of dosing should i start with?? I know you have alot of experience in this area! I'm also going into making a bone broth tomorrow. I have to get my gut where i can eat meat and a wider range of veg!! I am seeing results with my elimination diet but i can tell i'm not getting proper calories or vitamins

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Post  LittleFighter Thu Jul 05, 2012 3:57 pm

gg4545 wrote:yeah i know lol info looks good though!!

About the lacto gg what kind of dosing should i start with?? I know you have alot of experience in this area! I'm also going into making a bone broth tomorrow. I have to get my gut where i can eat meat and a wider range of veg!! I am seeing results with my elimination diet but i can tell i'm not getting proper calories or vitamins

Avoid Wheat and Milk. Those are commonly problematic. Milk is bad for me gives me skin problems after some time abusing it. In theory after a long time, vitamins and good bacteria you can regain tolerance.

The dose of the problatic is not problematic. Take 1 capsule per day and see what it does to your digestion like improved elimination. That's the normal dose, a higher dose doesn't hurt but may be unnecessary.

All the dietary recommendations promoted here (most of them) like avoiding vegetable oils, hydrogenated fat, processed foods, etc is just right. Follow those sensible recommendations.
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Post  987 Sat Jul 07, 2012 2:30 pm

CausticSymmetry wrote:This is my belief also. For that reason, I've been advising many of my clients to take animal form vitamin A.

More info here:

http://healthyfixx.com/33/why-vitamin-a-is-more-important-than-you-think

Nice... Any product recommendations for animal A? Was that more about supplemental vitamin D3 or sun light derived D also? Thanks

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Post  CausticSymmetry Sat Jul 07, 2012 2:55 pm

Either of these is fine:

http://tinyurl.com/7t39lyo

or

http://tinyurl.com/74f2xek

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Post  987 Sat Jul 07, 2012 4:29 pm

Cant seem to find any Vitamin A through Iherb without soybean oil... I know it probably doesnt matter, but i just dont like consuming anything with soy.. W.e. Ill probably try it.

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Post  CF Sat Jul 07, 2012 4:59 pm

J987 wrote:Cant seem to find any Vitamin A through Iherb without soybean oil... I know it probably doesnt matter, but i just dont like consuming anything with soy.. W.e. Ill probably try it.

This one is not cheap but no soy. http://www.iherb.com/Carlson-Labs-Vitamin-A-10-000-IU-250-Soft-Gels/9363?=hil335

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Post  LittleFighter Fri Jul 20, 2012 4:32 pm


"They also suffer from a more serious subclinical problem. They can never cure their leaky gut due to chronic inflammation from infections. The reason for both of these clinical features is that they likely have a co morbid lack of Vitamin A in the diet to offset the raised supplemental Vitamin D3. Each cell in our body has 2 vitamin A receptors for every Vitamin D receptor. So as our vitamin D level rises, our endogenous Vitamin A source is used up even quicker. We need to make sure we are getting enough of the fat soluble Vitamin A too as Vitamin D3 goes up. These two vitamins are metabolically coupled. This is probably the most common reason people have persistent bloating and cannot clear H Pylori or Candida infections from their guts when they transition to a paleo template."

Dr. Jack Kruse

http://jackkruse.com
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Post  Balthier Sat Jul 21, 2012 7:09 am

is retinyl palmitate as good as retinol seems like most use this instead(I thin that one cs linked by source naturals isretinyl too unless I'm reading it wrong?) or sometimes a combination?

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Post  LittleFighter Sun Jul 22, 2012 9:14 pm


Vitamin A and testosterone...

http://www.westonaprice.org/mens-health/vitamin-a-forgotten-bodybuilding-nutrient

Vitamin A and the THYROID, given how much importance it is given in the theories exposed by many...

http://www.westonaprice.org/fat-soluble-activators/vitamin-a-saga

Foods high in vitamin A are especially important for diabetics and those suffering from thyroid conditions. In fact, the thyroid gland requires more vitamin A than the other glands, and cannot function without it.8 And a diet rich in vitamin A will help protect the diabetic from the degenerative conditions associated with the disease, such as problems with the retina and with healing.




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Post  GreatDiscovery Sun Jul 22, 2012 10:10 pm

Afaxin 25,000 units and 50,000 units contains Retinol palmitate or Vitamin A which is used for the treatment of vit A deficiency.

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