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Estrogen Dominance or High DHT/5AR? Thoughts on DIM...
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Estrogen Dominance or High DHT/5AR? Thoughts on DIM...
Without actually having any hormone profiles done on myself, I have believed myself to be estrogen dominant based on symptoms: central obesity sparing the limbs, excess tissue on the chest, inability to lose weight despite lifestyle changes, low T symptoms including anxiety, lack of aggression, fatigue.
I realize, however, that after taking DIM and seeing a loss of libidio and testicular pain, that estrogen may not be the problem, and in fact, DIM could be compounding the estrogen problem if that is in fact what I'm dealing with.
So my questions are:
1) Can some of the symptoms of high estrogen (central obesity) actually be the result of high 5AR and DHT? I realize that some of these symptoms are actually symptoms of high cortisol (which will likewise lower T), and that high 5AR and high DHT can adversely effect peripheral cortisol metabolism, leading to high ACTH and high cortisol.
2) If DIM is adversely effecting my libido, does this support the idea that my estrogen isn't truly a problem? There are some studies showing that DIM can act as a potent estrogen and increase transcription of estrogen related genes.
(I know that this is something I need to have checked out by an endo for sure, but in the meantime, information would be wonderful).
http://www.ncbi.nlm.nih.gov/pubmed/10653634?dopt=Abstract
http://www.ncbi.nlm.nih.gov/pubmed/11162784?dopt=Abstract
http://www.nature.com/oby/journal/v14/n4/full/oby200675a.html
http://suppversity.blogspot.com/2012/01/intermittent-thoughts.html
I realize, however, that after taking DIM and seeing a loss of libidio and testicular pain, that estrogen may not be the problem, and in fact, DIM could be compounding the estrogen problem if that is in fact what I'm dealing with.
So my questions are:
1) Can some of the symptoms of high estrogen (central obesity) actually be the result of high 5AR and DHT? I realize that some of these symptoms are actually symptoms of high cortisol (which will likewise lower T), and that high 5AR and high DHT can adversely effect peripheral cortisol metabolism, leading to high ACTH and high cortisol.
2) If DIM is adversely effecting my libido, does this support the idea that my estrogen isn't truly a problem? There are some studies showing that DIM can act as a potent estrogen and increase transcription of estrogen related genes.
(I know that this is something I need to have checked out by an endo for sure, but in the meantime, information would be wonderful).
http://www.ncbi.nlm.nih.gov/pubmed/10653634?dopt=Abstract
http://www.ncbi.nlm.nih.gov/pubmed/11162784?dopt=Abstract
http://www.nature.com/oby/journal/v14/n4/full/oby200675a.html
http://suppversity.blogspot.com/2012/01/intermittent-thoughts.html
AS54- Posts : 2367
Join date : 2011-08-12
Age : 35
Location : MI
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