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Natural treatments for vitiligo?
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Natural treatments for vitiligo?
Since I was a teenager, I've had two small spots (one on each side of the chest) affected by vitiligo (hypopigmentation of the skin caused by autoimmune destruction of melanocytes). Recently I noticed that there's another spot appearing on my cheek, and it appears to be growing. Are there any natural treatments for this?
imprisoned-radical- Posts : 493
Join date : 2011-08-10
Re: Natural treatments for vitiligo?
Are you sure it's vitiligo? I also have this, but a doctor told me it was lichen schlerosus, another similar disease.
The more experienced doctor that said it is vitiligo gave me a cream (chemical) to apply 2 times a day. Also, she told me there a thyroid problem in some vitiligo pacients and I got the thyroid checked but the results seem to be normal: ANTI-TPO=14; T3=1.5; FT4=17;TSH=2; AAN=0.1, AntiReceptorTSH<0.3,Antithyroglobulin=14.
I found this on danny roddy's site:
Decreased proinflammatory cytokine production by peripheral blood mononuclear cells from vitiligo patients following aspirin treatment.
Zailaie MZ.
Source
The Vitiligo Unit, King Abdul-Aziz University Medical Center, PO Box 80170, Jeddah 21589, Kingdom of Saudi Arabia. mzailaie@kaau.edu.sa
Abstract
OBJECTIVE:
Limited studies have shown that treatment of cells with aspirin modulates their cytokine production. Consequently, the aim of the present study is to investigate the pattern of important proinflammatory cytokines production by stimulated peripheral blood mononuclear cells (PBMC) from patients with active vitiligo following long-term treatment with low-dose oral aspirin.
METHODS:
The study was conducted at the Vitiligo Unit, King Abdul-Aziz University Medical Center, Jeddah, Kingdom of Saudi Arabia between March and October 2003. Thirty-two patients (18 females and 14 males) with non-segmental vitiligo were divided into 2 equal groups, one group received a daily single dose of oral aspirin (300 mg) and the other group received placebo for a period of 12 weeks. The concentrations of interleukin (IL)-1beta, IL-6, IL-8 and tumor necrosis factor-alpha (TNF-alpha) were determined in the supernatant of isolated cultured PMBC after being stimulated with bacterial lipopolysaccharide (LPS), before the start of aspirin treatment and at end of treatment period. Cytokine levels were measured using the quantitative sandwich enzyme-linked immunosorbent assay (ELISA) technique, utilizing commercially available kits.
RESULTS:
The proinflammatory cytokine production by the PBMC of patients with active vitiligo was significantly increased compared to normal controls. Thus, the relative percentage increase in the production of IL-1beta, IL-6, IL-8 and TNF-alpha was: 39.4%, 110.5% (p<0.05), 91.5% (p<0.01), and 37% (p<0.05). At the end of treatment, proinflammatory cytokine production in the aspirin-treated group of active vitiligo patients was significantly decreased compared to the placebo group. Thus, the relative percentage decrease in the production of IL-1beta IL-6, IL-8 and TNF-alpha was: 42.5%, 45.2% (p<0.05), 30.8% (p<0.01), and 50.6% (p<0.05). The vitiligo activity was arrested in all aspirin-treated patients, while 2 patients demonstrated significant repigmentation.
CONCLUSION:
Chronic administration of low-dose oral aspirin can down-regulate the PBMC proinflammatory cytokine production in active vitiligo with concomitant arrest of disease activity.
Since he's saying that aspirin is good for hair and it is only 300mg/day for 3 months, I am going to give it a shot.
I looked on the net for natural treatments but I could not find much about it...
The more experienced doctor that said it is vitiligo gave me a cream (chemical) to apply 2 times a day. Also, she told me there a thyroid problem in some vitiligo pacients and I got the thyroid checked but the results seem to be normal: ANTI-TPO=14; T3=1.5; FT4=17;TSH=2; AAN=0.1, AntiReceptorTSH<0.3,Antithyroglobulin=14.
I found this on danny roddy's site:
Decreased proinflammatory cytokine production by peripheral blood mononuclear cells from vitiligo patients following aspirin treatment.
Zailaie MZ.
Source
The Vitiligo Unit, King Abdul-Aziz University Medical Center, PO Box 80170, Jeddah 21589, Kingdom of Saudi Arabia. mzailaie@kaau.edu.sa
Abstract
OBJECTIVE:
Limited studies have shown that treatment of cells with aspirin modulates their cytokine production. Consequently, the aim of the present study is to investigate the pattern of important proinflammatory cytokines production by stimulated peripheral blood mononuclear cells (PBMC) from patients with active vitiligo following long-term treatment with low-dose oral aspirin.
METHODS:
The study was conducted at the Vitiligo Unit, King Abdul-Aziz University Medical Center, Jeddah, Kingdom of Saudi Arabia between March and October 2003. Thirty-two patients (18 females and 14 males) with non-segmental vitiligo were divided into 2 equal groups, one group received a daily single dose of oral aspirin (300 mg) and the other group received placebo for a period of 12 weeks. The concentrations of interleukin (IL)-1beta, IL-6, IL-8 and tumor necrosis factor-alpha (TNF-alpha) were determined in the supernatant of isolated cultured PMBC after being stimulated with bacterial lipopolysaccharide (LPS), before the start of aspirin treatment and at end of treatment period. Cytokine levels were measured using the quantitative sandwich enzyme-linked immunosorbent assay (ELISA) technique, utilizing commercially available kits.
RESULTS:
The proinflammatory cytokine production by the PBMC of patients with active vitiligo was significantly increased compared to normal controls. Thus, the relative percentage increase in the production of IL-1beta, IL-6, IL-8 and TNF-alpha was: 39.4%, 110.5% (p<0.05), 91.5% (p<0.01), and 37% (p<0.05). At the end of treatment, proinflammatory cytokine production in the aspirin-treated group of active vitiligo patients was significantly decreased compared to the placebo group. Thus, the relative percentage decrease in the production of IL-1beta IL-6, IL-8 and TNF-alpha was: 42.5%, 45.2% (p<0.05), 30.8% (p<0.01), and 50.6% (p<0.05). The vitiligo activity was arrested in all aspirin-treated patients, while 2 patients demonstrated significant repigmentation.
CONCLUSION:
Chronic administration of low-dose oral aspirin can down-regulate the PBMC proinflammatory cytokine production in active vitiligo with concomitant arrest of disease activity.
Since he's saying that aspirin is good for hair and it is only 300mg/day for 3 months, I am going to give it a shot.
I looked on the net for natural treatments but I could not find much about it...
dreft- Posts : 213
Join date : 2011-04-23
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