The essential oils of Chamaecyparis obtusa promote hair growth

Fitoterapia. 2010 Jan;81(1):17-24. Epub 2009 Jul 2.
The essential oils of Chamaecyparis obtusa promote hair growth through the induction of vascular endothelial growth factor gene.
Lee GS, Hong EJ, Gwak KS, Park MJ, Choi KC, Choi IG, Jang JW, Jeung EB.

Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 361-763, Republic of Korea.

Chamaecyparis obtusa (C. obtusa) is a conifer in the cypress family Cupressaceae, native to northeast Asia. The essential oils of C. obtusa have antibacterial and antifungal effects and several products such as hygienic bands, aromatics, and shampoos contain these oils as a natural source of antimicrobial/antifungal agents. Interestingly, some consumers suffering from baldness and/or other forms of hair loss have reported a hair growth promoting effect of shampoos containing these oils. In the present study, the hair growth promoting effect of C. obtusa oils was elucidated in an animal model. C. obtusa oils promoted the early phase of hair growth in shaved mice. In addition, we examined the molecular effect of C. obtusa oils on the regulation of hair morphogenesis and hair growth using the human keratinocyte cell line HaCaT. In the current study of hair growth regulating genes, the expressions of vascular endothelial growth factor (VEGF), transforming growth factor (TGF beta 1), and keratinocyte growth factor(KGF) have been analyzed by real-time PCR in HaCaT cells. The essential oils of C. obtusa were divided into seven fractions for treatment of HaCaT cells. VEGF transcripts were induced by fractions 6 and 7; however, TGF beta 1 and KGF mRNA levels were unchanged by C. obtusa oils or fractions. Fraction 7 was separated into seven sub-fractions and studied further. Sub-fractions E and D significantly increased VEGF and KGF gene expression without up-regulating the hair growth inhibition factor, TGF beta 1. The components of the two sub-fractions were further analyzed by gas chromatography and mass spectrometry. Cuminol, eucarvone, and calamenene were common to these two sub-fractions, although the effects of these individual components were not determined. Taken together, these results suggest that C. obtusa oils promote hair growth in an animal model and a positive regulator of hair growth, VEGF, was induced by particular components of these oils.

Way to IH.

M

Did a quick search on this and found some postings about it from back in 2009 but haven't heard about any successes or seen new products based on this. You gonna give it a try CS?

Did some web search for this. Looks like this might be difficult to get.

"11. Hinoki wood oil. Since 1982 the Japanese government has protected Chamaecyparis obtusa where the oil is extracted from, and has only allowed the use of trees that have died naturally, or which have been recycled from the rebuilding of temples. Therefore the oil is produced from the steam distillation of the chipped wood and sawing wastes of the Hinoki tree legally obtained, and buyers should seek documented proof of legality if buying from a Japanese source. There may now also be some limited Chinese production of this oil. "

From: http://www.heavenscentoils.net/endangered.htm