Itching from proteolytic enzymes?

Some days ago I got on Iosol and some proteolytic enzymes.Specifically serrapeptase and bromelain
I combine 1 cap of bromelain + 1 cap of serrapeptase twice per day.
I noticed an extreme itching everywhere on the body mainly on my trunk and thighs.
The itching is unbearable ,I can't help it if I don't scratch my self continuously.It lasts many hours.
At first I thought it was the Iosol but today ,just some mins after my dose of enzymes the itching appeared again.
I read the usage instructions of my serrapeptase and in the side effects it mentions clearly : itching
Funny thing is I've used before both serrapeptase and bromelain with no side effects at all but that's the first time i combined them.

What does that intense itching mean? Will it subside or i should quit?
Anone has any similar experience? IH?

@Jdp : you use them regularly in high doses.Have you read anything regarding sides?

edony - Which brand of enzymes were you using?