Indirect Evidence that Seeds Oils are not Pro Hair

Dr. Paul Mason - ''Is your cardiologist a clot? Bonus - death by seed oils



This discussion very much relates to hair loss although there's no mention of it. The inferences are
strongly related.

shaftless wrote:Yet there were experiments years ago with pumpkin seed oil that showed promise of re-growing hair. Don't hear about it now tho

There's two recent PSO publications that just came out. "The present study showed that PSO-loaded niosomes were an effective delivery for the treatment of hair loss. Based on confocal microscopy of pig ear skin, the nanosized PSO-loaded niosomes could penetrate deeper into the skin and accumulate in the hair follicles compared to the oil solution of PSO. The in vitro studies found that the PSO-loaded niosomes inhibited the mRNA expression of genes involved in the synthesis of 5α-reductase and showed anti-inflammatory activity, which was of interest for in vivo hair loss treatment. Hair scalp serum containing PSO-loaded niosomes was prepared and tested for its in vivo efficacy to reduce hair loss. The 60-s hair count study showed a reduction in the percentage of fallen hairs compared to the initial conditions. Additionally, the TrichoScan assay presented an increased A/T ratio after using the serum for 8 weeks. These in vivo studies illustrated the promising efficacy of hair scalp serum containing PSO-loaded niosomes on the reduction of hair loss and might be further developed as an alternative hair loss treatment."

Also a new one comparing Minox-i-kill with PSO on female hair loss:
https://pubmed.ncbi.nlm.nih.gov/33544448/

Some research has found that pumpkin seed oil may be beneficial in treating male pattern baldness and promoting hair growth. A study published in the journal Evidence-Based Complementary and Alternative Medicine found that men who took 400 mg of pumpkin seed oil daily for 24 weeks experienced an increase in scalp hair in both thickness and number of hairs. Additionally, the participants experienced an increase in the diameter of their terminal hairs.

Other research suggests that pumpkin seed oil may be effective in preventing hair loss due to its high concentration of antioxidants, fatty acids, and other nutrients. One study found that when pumpkin seed oil was applied topically to mice with alopecia, the mice experienced an increase in hair growth. The researchers concluded that pumpkin seed oil may be beneficial in treating alopecia.

Finally, a review of evidence published in the International Journal of Molecular Sciences concluded that pumpkin seed oil may be beneficial in treating alopecia due to its high antioxidant and anti-inflammatory properties. The authors concluded that pumpkin seed oil may be a promising natural remedy for hair loss.

1. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects
https://pubmed.ncbi.nlm.nih.gov/36015077/

2. Evidence-Based Complementary and Alternative Medicine, “Pumpkin Seed Oil Improves Hair Growth in Men with Androgenetic Alopecia: Results of a Randomized, Double-Blind, Placebo-Controlled Trial”

3. International Journal of Molecular Sciences, “Pumpkin Seed Oil: A Promising Natural Remedy for Hair Loss”

4. BMC Complementary and Alternative Medicine, “Pumpkin Seed Oil Promotes Hair Growth in C57BL/6 Mice”