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setipiprant...a not so far away cure? EmptyYesterday at 11:16 am by CausticSymmetry

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setipiprant...a not so far away cure?

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Post  shaftless Wed Feb 18, 2015 3:28 pm

Two pharmaceutical companies are teaming up with the university of pennsylvania for rights to the drug setipiprant. It is an experimental asthma amd rhinitis drug and has already went thru quite a bit of testing. Since the u of penn and doctor cotsarelis is involved it appears his theories on hair loss is being taken seriously. Setipiprant is a potent selective pgd2 receptor antagonist. Maybe the cure isn't so far off as we think.

shaftless

Posts : 1344
Join date : 2012-08-12

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Post  shaftless Thu Feb 19, 2015 2:14 am

Here's the link if anyone is interested...

http://files.shareholder.com/downloads/AMDA-MFNLA/3961447985x0x808462/68E997C5-DA72-40B4-8BD5-9DFD765BFA2E/KYTHERA



If it can be made into a topical then side effects would be mininmum, hopefully.

shaftless

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Post  iuyyighghghgkh Thu Feb 19, 2015 3:48 am

This misses a lot out, especially methylation and mitochondria,
and takes some information from hairloss-research.org , to simplify it

block mmp9 , mmp2 :

ecklonia cava
also the things mentioned in this pdf file, which also help hair loss , and explains mmp9
http://www4.dr-rath-foundation.org/pdf-files/cancerresearch.pdf

block tgfbeta 1 :

taurine

block NF-κB :

curcumin/resveratrol

block pgd2 :

tocotrienols

declog and decalcify arteries with k2, silica and msm and vitamin c

iuyyighghghgkh

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Post  Kazbar Thu Feb 19, 2015 8:38 pm

Isn't blocking PGD2 actually bad?

Kazbar

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Post  shaftless Fri Feb 20, 2015 3:25 am

No. Blocking pge2 is bad since it helps stimulate hair growth. Pgd2 is what tells the hair to stop growing.

shaftless

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