Search
Check Out Our Sponsors
Latest topics
Possible role of hyperinsulinemia and insulin resistance in lower vitamin d levels in overweight and obese patients.
Page 1 of 1
Possible role of hyperinsulinemia and insulin resistance in lower vitamin d levels in overweight and obese patients.
http://www.ncbi.nlm.nih.gov/pubmed/23509804
Abstract
A cohort of 66 healthy overweight and obese patients, 53 women and 13 men were examined. Waist circumference and fasting 25(OH)D, insulin, glucose, lipid (cholesterol, HDL cholesterol, and triglyceride), C-reactive protein (CRP), and complement 3 (C3), and 4 (C4) serum concentrations were measured. Insulin resistance was assessed by the homeostasis model assessment (HOMAIR). Results. 25(OH)D levels showed a significant negative correlation with BMI (P < 0.01), waist circumference (P < 0.05), fasting insulin (P < 0.01), HOMAIR (P < 0.01), triglycerides (P < 0.01), CRP (P < 0.01), C3 (P < 0.05), and C4 (P < 0.05). Multiple regression analyses were performed with 25(OH)D as the dependent variable and BMI (or waist circumferences), fasting insulin (or HOMAIR), triglycerides, and CRP (or C3 or C4) as independent variables. Only insulin or HOMAIR maintained a significant independent association with 25(OH)D levels, whereas vitamin D did not maintain a significant independent association with CRP or C3 or C4 concentrations. Conclusions. The present study, performed in overweight and obese subjects, shows that 25(OH)D levels are negatively associated with inflammatory parameters such as CRP and C3 and C4 levels, but not independently of BMI, body fat distribution, insulin levels, or insulin resistance. Our results suggest that hyperinsulinemia and/or insulin resistance are directly responsible for decrease of 25(OH)D levels in obesity.
_________________
Immortal Hair Supplement Line - Ortho Nutrition
Antioxidant Boost (Resveratrol, Curcumin, Sulforaphane)
R-ALA
Ecklonia Cava
Krill Oil
Decalcify
Rejuvaplex Topical
Other
Ubiquinol
ALCAR
Liv 52
Iodine
Ashwagandha
SUPERFOODS: Energy First and Sun Warrior Protein, Dessicated Liver, Concentrace, Colostrum, Brewers Yeast, Fermented Cod Liver & High Vitamin Butter Oil
scottyc33- Posts : 1150
Join date : 2008-08-11
Similar topics
» Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review
» Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in alopecia areata patients.
» The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia
» The role of psychological factors and serum zinc, folate and vitamin B levels in the aetiology of trichodynia
» The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia
» Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in alopecia areata patients.
» The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia
» The role of psychological factors and serum zinc, folate and vitamin B levels in the aetiology of trichodynia
» The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia
Page 1 of 1
Permissions in this forum:
You cannot reply to topics in this forum
|
|
Fri May 17, 2024 7:01 am by Atlas
» zombie cells
Sat May 11, 2024 6:54 am by CausticSymmetry
» Sandalore - could it be a game changer?
Wed May 08, 2024 9:45 pm by MikeGore
» *The first scientific evidence in 2021 that viruses do not exist*
Tue May 07, 2024 4:18 am by CausticSymmetry
» China is at it again
Tue May 07, 2024 4:07 am by CausticSymmetry
» Ways to increase adult stem cells
Mon May 06, 2024 5:40 pm by el_llama
» pentadecanoic acid
Sun May 05, 2024 10:56 am by CausticSymmetry
» Exosome Theory and Herpes
Fri May 03, 2024 3:25 am by CausticSymmetry
» Road to recovery - my own log of everything I'm currently trying for HL
Tue Apr 30, 2024 1:55 pm by JtheDreamer