Baldness Cure: Low Dose Naltrexone?

MilBA Wed Aug 31, 2011 12:40 pm

Interesting post -

"Naltrexone can be used to block opioids and provide the basis for treatment for drug abuse, but in low doses (LDN) it provides a paradoxical increase in natural endorphins that reverses inflammation and provides an effective treatment for autoimmune diseases, e.g. MS."

http://coolinginflammation.blogspot.com/2011/08/baldness-cure-low-dose-naltrexone.html

abc123 Wed Aug 31, 2011 1:52 pm

I like this guys blog but that was a rather unimpressive post.

tonyj Wed Aug 31, 2011 5:05 pm

I think CS thought it might work with idiopathic AA, and I think one or two people at AlopeciaWorld are trying it based upon the recommendation of their doctor. Her doctor suspected that LDN would reverse the AA based on anecdotal evidence on MS, RA and the study at Penn State by Dr Smith, Professor of Medicine ( Naltrexone Therapy Improves Activity and Promotes Mucosal Healing in Active Crohnâ€™S Disease: a Placebo-Controlled Trial ). It's been 4 months and the update is that AA has not progressed, but this damn AA is so unpredictable.

ubraj Thu Sep 01, 2011 3:11 am

tonyj wrote:this damn AA is so unpredictable.

There is a site devoted to topical Iodine or Iodide or white Iodine (I forget which) and many reported great results with alopecia areata. PUFA (blue UV light) is also a good treatment that people have used

I assume this is why while keeping in mind that vaccines is said to make one more susceptible to hypomethylation defects. Is said from normal 15% of population to 50% of population when vaccinated and thus body will have hard time clearing similar issues (retroviruses).

Immunization and Bacterial Pathogens in the Oropharynx as Risk Factors for Alopecia Areata.

Morales-Sánchez MA, Domínguez-Gómez MA, Jurado-Santa Cruz F, Peralta-Pedrero ML.

Centro Dermatológico Dr. Ladislao de la Pascua, México Distrito Federal, México.

Abstract
INTRODUCTION: Alopecia areata is an autoimmune inflammatory disease affecting the hair follicles. Researchers are currently interested in whether the presence of bacterial pathogens and/or a history of immunization can trigger an autoimmune response in patients who are genetically predisposed. OBJECTIVES: This study aimed to determine whether there is an association between the development of alopecia areata and throat carriage of bacterial pathogens or a history of immunization. MATERIAL AND METHODS: Sixty-five men and women with alopecia areata and 65 control patients with other skin diseases were studied at the Dr Ladislao de la Pascua Dermatology Clinic between September 2008 and February 2009. The patients ranged in age from 18-59 years. Patients with scalp diseases were excluded from the control group. In all cases, the patient was questioned about immunizations received in the previous 6 months, and a throat swab was cultured. RESULTS: A history of immunization (odds ratio [OR], 3.3; 95% confidence interval [CI], 1.6-6.7; P=.001), the presence of bacterial pathogens in the oropharynx (OR, 2.6; 95% CI, 1.1-6.2; P=.033), and being a carrier of Streptococcus pyogenes (OR, 2.1; 95% CI, 1.7-2.5; P=.042) were risk factors for alopecia areata. Klebsiella pneumoniae, S. pyogenes, Pseudomonas aeruginosa, Streptococcus pneumoniae, Serratia marcescens and Escherichia coli were isolated from cultures. CONCLUSIONS: This is the first study to show an association between alopecia areata and throat carriage of bacterial pathogens or history of immunization, as risk factors for development of the disease. Given the characteristics of our study population, the association appears valid for patients with less than 25% hair loss and a course of disease under 1 year.

CausticSymmetry Thu Sep 01, 2011 5:29 am

oirvblp - Thanks for this info, interesting stuff.

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