Estradiol and P-45

Does lowered levels of Estradiol generate any positive effects on the scalp hair follicles? Any sides?

According to Androgenetic Alopecia Administration: "Young women have much higher levels of Cytochrome P-45 alpha0 aromatase in frontal follicles than men, and hair biologists believe the female scalp may have two-fivefold greater amounts of aromatase versus male scalp. This, they believe, may also explain why women may have a sparing of the frontal hairline in androgenetic alopecia, and also why they have a less severe pattern of hair loss than men."
If this is reality, how can this information be helpful for us men?

The "famous" Bryan replied: "What I find highly amusing about all this is the fact that from time to time over the years, guys have posted about the goofy theory that estrogen actually CAUSES balding, and they're busy trying to find some way to get Arimidex to reduce their estrogen, or find some natural product that might be able to do that. That site hairloss-research.org has been the main proponent of that nutty idea for several years, and they've been trying to sell chrysin supplements to anybody who will fall for it!"

- Comments?

Misirlou - Myself and others have had a few discussions with him, but no opinions on either side had changed. The short answer is that he had over simplified the context of the question.

In younger men, estrogen is not a problem, but into the 30's, 40's and beyond estrogen makes a serious impact.

As women age, their testosterone drops, and hence their estrogen drops too, since it is made from testosterone. Women hair loss becomes more of a factor then.

As men age, their testosterone drops, while their estrogen rises. Fungi and yeast work very similarly to cancer. Cancer actually is a fungus, and the reason for this statement is that estrogen fuels neoplastic changes and increases proliferation of yeasts, fungi, etc. DHT in older men is synonymous with high estrogen, that is to say, that elevated DHT is a symptom of high estrogen in older men. Levels of matrix metalloproteinase (MMP)-9 are regulated by estrogen levels.

To make matters more complicated, not all estrogen is bad. 7-HMR lignans are weaker forms of estrogens that displace stronger estrogens (E2). PM Kudzu increases estriol, a weak estrogen and help "regulate" estrogens in the body. DIM, helps break down estrogen metabolites and decreases levels of matrix metalloproteinase (MMP)-9, it also happens to inhibit DHT.

http://cancerres.aacrjournals.org/cgi/content/full/67/7/3310

Pomegranate has weak forms of estrogen like molecules that degrade collagen enzymes such as MMP-9 and help reverse atherosclerosis.

Estrogen also fuels insulin resistance, specifically potent estrogen's. BPA or Bisphenol-A from certain plastics cause diabetes in small animals at a dose of only 10 micrograms.

Testosterone treatment is one of the most effective ways to treat heart disease and diabetes.