Protease Nexin-1 is in Human Dermal Papilla Cells is depressed by DHT

An old study but a new connection. Nexin is a plasmin activator and the following study confirms its expression is suppressed by DHT in the dermal papilla. If there is a way to spare Nexin-1 from DHT or to supply additional antiplasmin that may help counteract a primary mechanism in the miniaturization of the hair follicle.

http://www.nature.com/jid/journal/v113/n3/full/5603232a.html

Here's a review that contains additional data

http://www.john-libbey-eurotext.fr/fr/revues/medecine/ejd/e-docs/00/01/88/99/article.phtml

Could this be one reason why to why 5-AR inhibitors such as finasteride actually do work?