Check this Cayenne Pepper product out! 180,000 HU and Kombucha...

I'm definitely getting on this:

http://www.happyherbalist.com/index.asp?PageAction=VIEWPROD&ProdID=114

An excerpt:

Detailed Description

According to Traditional Chinese Medicine, Kombucha Hydrosol flavor is sour and bitter and its nature is warm. It enters the Liver and Stomach channels, and functions to scatters stasis, stops bleeding, resolves toxins, and kills parasites.

Dr. Christopher and later Richard Schultz report that the cayenne pepper benefit both the heart and the health of the entire circulatory system. Dr. Christopher, after extensive experience, believed that cayenne pepper delivers vital nutrients directly to the heart within seconds of proper use. He utilized the stimulating effects of cayenne to restore proper function to the heart in heart attack cases.

Clinical and anecdotal evidence strongly suggests that cayenne pepper can be utilized to carry other substances, such as herbs and other nutrients, into the bloodstream - and sometimes within seconds. Extensive clinical studies conducted with cayenne pepper and Ginko Biloba demonstrate that Ginko is 75% more effective when used with cayenne.

In order to maximize the benefits associated with cayenne pepper, a high quality product must be used, with a true rating of between 90,000 and 150,000 HU (heat units). Ours is 180,000 !

Holy shit!! 180,000 IU!!!!!

Nid Goodluck with that, this stuff will certaintly seperate the men from the boys.

I wonder if this is the stuff responsible for spontaneous self combustion!

The only thing spontaneously self-combusting will by my Candida.

I'll give feedback of course!

Nid, I thought you rid of your Candia using Zeolite???

I did, but then I stopped buying the Zeolite to cut down on expenses, and ate a good deal of crap for a while so I've still got it. However, I still feel far better than I did before I started battling Candida, and this last 10-day Master Cleanse that I did *really* swept out the Candida.

nidhogge - That's a pretty cool cocktail.

This might be a little over the top, but this Pure Cap has been around for some years.

http://www.hotsauceworld.com/purecap.html

500,000 STU's.

Holy bejesus!

Thanks IH, think I'll get adjusted to the 180,000 HU first and then work my way up there.

Vanilloid receptor signaling and capsaicin inhibitory effects

Contained in the human hair follicle is something known as the Vanillioid receptor-1 or "TRPV". Scientists have recently discovered that this Vanillioid receptor-1 is very significant for hair growth. The receptor can be signaled by certain processes so as to inspire new hair growth where there was previously very little. Alternatively, the signaling of this receptor can be inhibited by other agents, one of which is known as Capsaicin. Capsaicin is a chemical that is found in hot peppers can be used to de-activate the Vanilloid receptor and thereby regulate the growth of hair. Other proteins and genetic building blocks such as TGF-b2 have also been tested to see the affects on the Vanillioid receptor. So far, however, Capsaicin has proven to have the most potent effect.

The Vanillioid receptor-1 or "TRPV" as it is sometimes referred, can be activated in certain cells of the skin such as mast cells, glial cells, bronchial epithelial cells, uroepithelial cells and keratinocytes. When the TRPV expressing cells are activated in hair follicles, there is often a change in the cell proliferation of hair follicles. Scientists have experimented with these findings in order to discover not just the basic proliferation changes but the effects on hair elongation, pigmentation and growth cycle patterns of hair follicles.

A study was done in which hair follicles were first taken from a number of female patients who were undergoing facelift surgery. The hair follicles were individually measured at the start of the experiment so as to test for any changes that would come about later in the experiment. Some hair follicles were also examined to determine the presenceo f distribution of different proteins and cell receptors. The follicles were prepared under 24 different plates, treated with the various agents and often colored with certain pigments to determine various results.

Early in the experiment, scientists measured the protein and calcium changes in the hair follicles after they were combined with certain agents. Some proteins and calcium changes were discovered and documented in relation to their affect on hair growth. Scientists also measured other changes such as the proliferation change which came about in the presence of TRPV. This proliferation change was measured through a process known as flow cytometry.

On the human scalp, it was discovered that specific localized expression of TRPV existed in two important areas of the hair follicle. The most prominent area was found to be the outer root sheath or ORS and the less prominent area was the hair matrix. With these initial findings, scientists were able to focus their observations on other agents and the more specific effects that they had on TRPV and hair growth.

It was later discovered that the signaling of TRPV by certain proteins and chemical agents had a profound effect on the production of keratinocyte proliferation. With an increase in keratinocyte proliferation, there was a significant increase in hair growth and a change in growth characteristics. Once these initial discoveries were made, an alternate approach was ready for testing.

Capsaicin was added to the areas where TRPV had been originally expressed but, instead of getting positive changes as had first been the case, there was a reverse in the process of TRPV signaling. The Capsaicin inhibited the elongation of the hair follicles by slowing down the activity of the TRPV and keratinocyte proliferation in the follicles. The pigmentation was also depleted in the hair follicles when Capsaicin was applied.

Capsaicin was observed in relation to many features but only one feature remained unchanged by its effects. The in situ differentiation of the hair follicles was not affected by the Capsaicin. This differentiation was the only quality of the hair follicles that remained unaffected. Although scientists had discovered that Capsaicin could produce inhibitory effects on the TRPV in terms of the proliferation of hair follicles, the elongation and the pigmentation of the hair follicles, it had not affected the differentiation characteristics at all.

TGF-b2, was also experimented with in combination with the Capsaicin to see the resultant effect on the TRPV signaling. Scientists wanted to know if TGF-b2 would also have an inhibitory affect on hair growth and help along the work of the Capsaicin. In fact, the TGF-b2 showed a tendency to partially negate the effects of the Capsaicin. The hair growth was no longer inhibited as it had been by using the Capsaicin agent alone. Other experiments like this one have become an ongoing focus for scientists.

Other proteins and organic agents have been tested to determine the effects that different genes may have in TRPV signaling. Some of these agents include activin BA and matrix GLA-protein precursor. These studies into the effects of genetic manipulation in hair follicles promise new discoveries for patients who wish to remove unwanted hair and to inspire new growth in areas where there has been unwanted hair loss.

Vanilloid receptor signaling and capsaicin inhibitory effects references

* Bodo E, Biro T, Telek A, Czifra G, Griger Z, Toth BI, Mescalchin A, Ito T, Bettermann A, Kovacs L, Paus R. A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control. Am J Pathol. 2005 Apr;166(4):985-98. PMID: 15793280

Prague - That particular study generated a lot of discussion when it came out. Essentially this is cayenne pepper or capsaicin with human hair follicles bathing in them. Or to put it another way, the hair follicles are being literally soaked in a bath of capsaicin.

You'll want to check this out, because this is actually a brand new follow up to that 2005 study:

J Invest Dermatol. 2009 Feb;129(2):329-39.
Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology.
Tóth BI, Géczy T, Griger Z, Dózsa A, Seltmann H, Kovács L, Nagy L, Zouboulis CC, Paus R, Bíró T.

Department of Physiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

Transient receptor potential vanilloid-1 (TRPV1), originally described as a central integrator of nociception, is expressed on human epidermal and hair follicle keratinocytes and is involved in regulation of cell growth and death. In human pilosebaceous units, we had shown that TRPV1 stimulation inhibits hair shaft elongation and matrix keratinocyte proliferation, and induces premature hair follicle regression and keratinocyte apoptosis. In the current study, we have explored the role of TRPV1-mediated signaling in sebaceous gland (SG) biology, using a human sebocyte cell culture model (SZ95 sebocytes). Demonstrating that human skin SG in situ and SZ95 sebocytes in vitro express TRPV1, we show that the prototypic TRPV1 agonist, capsaicin, selectively inhibits basal and arachidonic acid-induced lipid synthesis in a dose-, time-, and extracellular calcium-dependent and a TRPV1-specific manner. Low-dose capsaicin stimulates cellular proliferation via TRPV1, whereas higher concentrations inhibit sebocyte growth and induce cell death independent of TRPV1. Moreover, capsaicin suppresses the expression of genes involved in lipid homeostasis and of selected proinflammatory cytokines. Collectively, these findings support the concept that TRPV1 signaling is a significant, previously unreported player in human sebocyte biology and identify TRPV1 as a promising target in the clinical management of inflammatory SG disorders (for example, acne vulgaris).

Another thing about Capsaicin is that it increases levels of calcitonin gene-related peptide (CGRP). CGRP increases IGF-1 (androgen blockage does not work unless IGF-1 levels are sufficient).

great info IH, thanks

i can do better : 1,000,00 HU

MP if you want it.

This may be of interest to you fellas--

In conjunction to the HairGen topical that I developed for Primordial Performance, another fella who independently developed an all-natural shampoo/conditioner approached Primordial with his products. He's been tweaking the formula for years and has terminalized a lot of hairs and spurred regrowth in just months! He's going to produce a batch for me at cost for 6-months, roughly $300 with shipping included. Guess what one of the primary ingredients are?

Capsaicin.

Wow. Is PP putting it into production then? Any word on other ingredients. Could always use a more effective shampoo.

Hapy--

I think they're waiting on a sample first so they can test it out on themselves over at PP to make sure it's customer-friendly. Ryan, the formulator, seems like a very knowledgeable and trustworthy guy in my conversations with him! I'd anticipate it getting picked up. I'll post the ingredient list soon for ya.