Immortal Hair
Would you like to react to this message? Create an account in a few clicks or log in to continue.

Search
 
 

Display results as :
 


Rechercher Advanced Search

Check Out Our Sponsors
Brought to you by
Hair Loss Forum
Navigation
 Portal
 Index
 Memberlist
 Profile
 FAQ
 Search
Latest topics
» Difficulty Swallowing During Sleep
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyToday at 4:25 am by shaftless

» Is it possible that testosterone levels have to be kept within a strict range?
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyMon Mar 25, 2024 3:08 am by Jean-Guy

» I am trying the Growband
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyMon Mar 25, 2024 2:57 am by Jean-Guy

» Hydrocurc
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyMon Mar 25, 2024 2:48 am by Jean-Guy

» questions about HGH
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyMon Mar 25, 2024 1:24 am by Dudard

» The Vital Role of NAD+ and Niacin in Longevity and Well-being
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptySat Mar 23, 2024 10:25 am by CausticSymmetry

» solar eclipse on april 8
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptySat Mar 23, 2024 1:53 am by shaftless

» Ways to increase adult stem cells
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyFri Mar 22, 2024 4:15 pm by Atlas

» How to increase FGF9
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. EmptyFri Mar 22, 2024 3:17 am by Atlas

Navigation
 Portal
 Index
 Memberlist
 Profile
 FAQ
 Search

Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.

Go down

Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway. Empty Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.

Post  CausticSymmetry Fri Sep 28, 2018 3:01 pm

Sci Rep. 2018 Sep 13;8(1):13785. doi: 10.1038/s41598-018-32138-2.
Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.
Zhou L1, Wang H1, Jing J1, Yu L1, Wu X1, Lu Z2.

Hair loss is characterized by a shortened hair anagen phase and hair follicles (HF) miniaturization. Morroniside is the most abundant iridoid glycoside extracted from Cornus officinalis and has various bioactivities in different cell functions and tissue regeneration. In this study, we investigated the effects and the underlying mechanism of morroniside on hair growth and regulation of HF cycle transition. Morroniside treatment significantly enhanced outer root sheath cell (ORSC) proliferation and migration in vitro. Additionally, morroniside upregulated Wnt10b, β-catenin and lef1. The enhanced ORSC proliferation and migration due to morroniside treatment were partly rescued by a Wnt/β-catenin signaling inhibitor, DKK1. Furthermore, in a hair-induced mouse model, morroniside injection accelerated the onset of anagen and delayed HF catagen, as shown by histological examination. Immunohistochemical analyses revealed that Wnt/β-catenin signaling pathway expression was upregulated in the HFs. These findings suggest that morroniside regulates HF growth and development partly through the Wnt/β-catenin signaling pathway and may be a potential treatment for hair loss.

Full Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137235/

_________________
My regimen
http://www.immortalhair.org/mpb-regimen

Now available for consultation (hair and/or health)
http://www.immortalhair.org/health-consultation
CausticSymmetry
CausticSymmetry
Admin

Posts : 14212
Join date : 2008-07-09

http://www.immortalhair.org/

Back to top Go down

Back to top

- Similar topics

 
Permissions in this forum:
You cannot reply to topics in this forum